Skip to main content
Log in

Synthesis and phagocytosis-stimulating activity of harmine and glaucine N-oxides

  • Published:
Pharmaceutical Chemistry Journal Aims and scope

The N-oxides of harmine and glaucine were obtained. The influence of the produced compounds on the phagocytosis-stimulating activity of human blood monocytes in vitro was studied. It was established that harmine and glaucine N-oxides have pronounced phagocytosis-stimulating properties.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. F. S. Sadritdinov and A. G. Kurmukov, Pharmacology of Plant Alkaloids and Their Use in Medicine [in Russian], FAN, Tashkent (1980).

    Google Scholar 

  2. A. Brossi (ed.), The Alkaloids. Chemistry and Pharmacology, Vol. XXI, ch. 5, 7, Academic Press, Paris, San Diego, San Francisco, etc. (1983).

    Google Scholar 

  3. P. J. Houghton, Y. Ren, and M.-J. Howes, Nat. Prod. Rep., 23(1), 181 – 232 (2006).

    Article  PubMed  CAS  Google Scholar 

  4. M. D. Mashkovskii, Drugs [in Russian], Vol. 15, Novaya Volna, Moscow (2006), p. 188.

    Google Scholar 

  5. V. N. Galankin, E. Kh. Yunuskhodzhaev, A. M. Tokmakov, and L. A. Mamedov, Arkhiv. Patol., 77(6), 260 – 265 (1987).

    Google Scholar 

  6. Zh. I. Avdeeva, N. M. Mazina, N. S. Vakhromeeva, and O. R. Krylov, Vestn. Dermatol. Venerol., 23(8), 356 – 359 (1990).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. K. Mukusheva.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 8, pp. 12 – 14, August, 2011.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mukusheva, G.K., Nurmaganbetov, Z.S., Ismagulova, N.M. et al. Synthesis and phagocytosis-stimulating activity of harmine and glaucine N-oxides. Pharm Chem J 45, 458–460 (2011). https://doi.org/10.1007/s11094-011-0654-3

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-011-0654-3

Key words

Navigation