Problems related to control of the expiration date of ready-to-use drugs and substances are always timely and can be solved by using differential scanning calorimetry (DSC). This method was used to monitor changes in the concentration of piracetam drug substance during experimental storage. An analysis of the DSC data showed that this technique can be used for determining objectively the expiration date of the drugs irrespective of the storage conditions.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 5, pp. 53 – 56, May, 2011.
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Boiko, B.N., Kolpakov, I.M. DSC monitoring of piracetam concentration stability during experimental storage. Pharm Chem J 45, 309–312 (2011). https://doi.org/10.1007/s11094-011-0623-x
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DOI: https://doi.org/10.1007/s11094-011-0623-x