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Synthesis and antiviral activity of several quinoline derivatives

Pharmaceutical Chemistry Journal volume 45, pages 267–269 (2011)Cite this article

The antiviral activity of 2-substituted and 2,6-disubstituted quinoline-4-carboxylic acids and their derivatives has been studied against orthopoxviruses on Vero and MK-2 cell cultures. High activity has been found for 2-(1,1′-biphenyl-4-yl)quinoline-4-carboxylic acid.

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Authors and Affiliations

  1. Samara State Technical University, Samara, Russia

    M. N. Zemtsova, A. V. Zimichev, P. L. Trakhtenberg, Yu. N. Klimochkin, M. V. Leonova & S. M. Balakhnin

  2. Vector, State Research Center for Virology and Biotechnology, Koltsova, Novosibirsk Oblast, Russia

    N. I. Bormotov, O. A. Serova & E. F. Belanov

Authors
  1. M. N. Zemtsova
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  2. A. V. Zimichev
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  3. P. L. Trakhtenberg
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  4. Yu. N. Klimochkin
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  5. M. V. Leonova
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  6. S. M. Balakhnin
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  7. N. I. Bormotov
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  8. O. A. Serova
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  9. E. F. Belanov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 45, No. 5, pp. 9 – 11,May, 2011.

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Zemtsova, M.N., Zimichev, A.V., Trakhtenberg, P.L. et al. Synthesis and antiviral activity of several quinoline derivatives. Pharm Chem J 45, 267–269 (2011). https://doi.org/10.1007/s11094-011-0613-z

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  • DOI: https://doi.org/10.1007/s11094-011-0613-z

Key words

  • quinolinecarboxylic acids
  • acid derivatives
  • biological activity