A method for improving the quality and increasing the yield of 2,7-dihydroxyfluorenone by using a rotor– stator apparatus in the process technology is described. The results can be used in the manufacturing of tilorone.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 44, No. 8, pp. 43 – 45, August, 2010.
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Kryukov, Y.A., Vasilishin, M.S., Ivanov, O.S. et al. Improved synthesis of 2,7-dihydroxyfluorenone in the manufacture of tilorone with application of a rotor—stator system. Pharm Chem J 44, 456–458 (2010). https://doi.org/10.1007/s11094-010-0489-3
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DOI: https://doi.org/10.1007/s11094-010-0489-3