A series of substituted 5-dialkylaminoacetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolines were synthesized by amination of the corresponding 5-chloroacetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolines. The acute toxicity, analgesic activity, and influence of the obtained compounds on the locomotor and exploratory activity in the open-field test were studied.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 43, No. 11, pp. 16 – 19, November, 2009.
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Krainova, G.F., Vikharev, Y.B., Anikina, L.V. et al. Synthesis and neurotropic activity of substituted 5-dialkylaminoacetyl-3a,4,5,9b-tetraydro-3H-cyclopenta[c]quinolines. Pharm Chem J 43, 606–609 (2009). https://doi.org/10.1007/s11094-010-0362-4
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DOI: https://doi.org/10.1007/s11094-010-0362-4