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Effects of lupane and oleanane β-enaminoketones on the number and morphology of white blood cells

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Pharmaceutical Chemistry Journal Aims and scope

The biological activity of several lupane and oleanane β-enaminoketones was studied. Comparative analysis of leukocyte reactions showed that both groups of triterpene derivatives had high biological activity on chronic administration and that their immunosuppressive activity resulted from toxic effects on lymphocytes.

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References

  1. T. G. Tolstikova, I. V. Sorokina, A. G. Tolstikov, et al., Bioorgan. Khimiya, 32(1), 42 – 55 (2006).

    CAS  Google Scholar 

  2. T. G. Tolstikova, I. V. Sorokina, A. G. Tolstikov, et al., Bioorgan. Khimiya, 32(3), 300 – 316 (2006).

    Google Scholar 

  3. I. A. Tolmacheva, L. V. Anikina, Yu. B. Vikharev, et al., Bioorgan. Khimiya, 34(1), 136 – 140 (2008).

    CAS  Google Scholar 

  4. I. A. Tolmacheva, L. V. Anikina, Yu. B. Vikharev, et al., Bioorgan. Khimiya, 34(4), 540 – 542 (2008).

    CAS  Google Scholar 

  5. Guidelines for Experimental (Preclinical) Studies of New Pharmacological Substances [in Russian], Pharmacology Committee, Ministry of Health of the Russian Federation, Moscow (2000).

  6. Laboratory Methods for Clinical Studies: A Handbook [in Russian], V. V. Men’shikov (Ed.), Meditsina, Moscow (1987).

  7. M.-L. Belenk’kii, Elements of the Quantitative Evaluation of Pharmacological Effects [in Russian], Meditsinskaya Literatura, Leningrad (1963).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Technical Chemistry, Urals Branch, Russian Academy of Sciences, Perm, Russia

    L. V. Anikina, I. A. Tolmacheva, Yu. B. Vikharev & V. V. Grishko

Authors
  1. L. V. Anikina
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  2. I. A. Tolmacheva
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  3. Yu. B. Vikharev
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  4. V. V. Grishko
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Corresponding author

Correspondence to L. V. Anikina.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 43, No. 7, pp. 6 – 8, July, 2009.

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Anikina, L.V., Tolmacheva, I.A., Vikharev, Y.B. et al. Effects of lupane and oleanane β-enaminoketones on the number and morphology of white blood cells. Pharm Chem J 43, 378–380 (2009). https://doi.org/10.1007/s11094-009-0318-8

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  • DOI: https://doi.org/10.1007/s11094-009-0318-8

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