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Electrochemical activity of alkaline salts of 5-amino-2,3-dihydrophthalazine-1,4-dione (luminol) and their ability to correct acid-base balance in cells

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The electrochemical reduction of alkaline salts of 5-amino-2,3-dihydrophthalazine-1,4-dione was studied. These salts were able to increase the cytoplasm pH of NIH 3T3 mouse embryo fibroblast cells, this being an indicator of cell activation.

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Authors and Affiliations

  1. OOO “VO-Delis”, Moscow, Russia

    V. M. Polosin & M. E. Solov’eva

  2. D. I. Mendeleev Russian Chemical-Technological University, Moscow, Russia

    V. T. Novikov

  3. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia

    M. E. Solov’eva & V. S. Akatov

Authors
  1. V. M. Polosin
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  2. V. T. Novikov
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  3. M. E. Solov’eva
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  4. V. S. Akatov
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 10, pp. 29–31, October, 2008.

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Polosin, V.M., Novikov, V.T., Solov’eva, M.E. et al. Electrochemical activity of alkaline salts of 5-amino-2,3-dihydrophthalazine-1,4-dione (luminol) and their ability to correct acid-base balance in cells. Pharm Chem J 42, 579–581 (2008). https://doi.org/10.1007/s11094-009-0182-6

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  • DOI: https://doi.org/10.1007/s11094-009-0182-6

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