Quantitative determination of the total content of flavonoids in Flavozid and Immunoflazid syrups

Pharmaceutical Chemistry Journal volume 42, pages536–538(2008)Cite this article

New syrup compositions Flavozid and Immunoflazid that contain 2% Proteflazid (ethanol extract of wild Deschampsia caespitosa L. and Calamagrostis epigeios L.) have been developed. The total content of flavonoids in both syrups is of the level of 4–6 µg/mL, which complicates the development of an analytical method. A new method for quantitative determination of flavonoids in the aforementioned syrups has been developed on the basis of differential UV spectrophotometry of their complexes with aluminum chloride. The proposed method is introduced into the Manufacturer's Pharmacopoeic Article for the syrups.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

US$ 39.95

Tax calculation will be finalised during checkout.

References

  1. 1.

    N. V. Nesterova, N. S. Dyachenko, V. P. Atamanyuk, et al., Anal. Mechnik. Inst. (Kharkiv), No. 4–5, 151–152 (200).

  2. 2.

    A. S. Priluts'kii, D. A. Lesnichenko, E. A. Mailyan, et al., Immunology and Allergology [in Ukrainian], Kyiv (2004), Vol. 2, 7–8.

    Google Scholar 

  3. 3.

    N. Nesterova, N. Diachenko, V. Atamaniuk, et al., Antiviral. Res. A, 69, 105 (2004).

    Google Scholar 

  4. 4.

    Rutin, Standard Sample, TU 64-4-127-96.

Download references

Author information

Affiliations

  1. Institute of Pharmacology and Toxicology, National Academy of Medical Sciences of Ukraine, Kiev, Ukraine

    O. V. Vishnevskii & V. P. Atamanyuk

Authors
  1. O. V. Vishnevskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. P. Atamanyuk
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to O. V. Vishnevskii.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 9, pp. 40–42, September, 2008.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Vishnevskii, O.V., Atamanyuk, V.P. Quantitative determination of the total content of flavonoids in Flavozid and Immunoflazid syrups. Pharm Chem J 42, 536–538 (2008). https://doi.org/10.1007/s11094-009-0176-4

Download citation

Keywords

  • Flavonoid
  • Quercetin
  • Rutin
  • Glacial Acetic Acid
  • Aluminum Chloride