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Synthesis and antimicrobial activity of methyl esters of 2-(het)arylamino-4-oxo-Z-2-butenoic acids, their structural analogs, and conversion products

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Pharmaceutical Chemistry Journal Aims and scope

Synthesis of a small library of compounds containing an aminovinylketone fragment is described. Results of studying their antibacterial activity against S. aureus ATCC 6538-P and E. coli ATCC 25922 are reported.

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, Perm, Russia

    A. A. Boteva, O. P. Krasnykh, S. S. Dubrovina, M. I. Vakhrin, E. B. Babushkina, T. F. Odegova & I. V. Solova

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  1. A. A. Boteva
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  2. O. P. Krasnykh
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  3. S. S. Dubrovina
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  4. M. I. Vakhrin
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  5. E. B. Babushkina
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  6. T. F. Odegova
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  7. I. V. Solova
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Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 8, pp. 12–15, August, 2008.

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Boteva, A.A., Krasnykh, O.P., Dubrovina, S.S. et al. Synthesis and antimicrobial activity of methyl esters of 2-(het)arylamino-4-oxo-Z-2-butenoic acids, their structural analogs, and conversion products. Pharm Chem J 42, 452–455 (2008). https://doi.org/10.1007/s11094-008-0160-4

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  • DOI: https://doi.org/10.1007/s11094-008-0160-4

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