Abstract
Allyl esters of 2-thiocyanato-2-methyl-3-arylpropionic acids exhibit pronounced antibacterial activity with respect to various test strains of staphylococci, colon bacilli, aerobic bacilli, and yeast fungi. The maximum activity is observed for compounds containing chlorine or bromine atoms at the aromatic nucleus.
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B. D. Grishchuk, P. M. Gorbovoi, and N. I. Ganishchak, Zh. Org. Khim., 59(5), 1969–1972 (1989).
P. M. Gorbovoi, V. N. Nivalov, N. G. Prodanchuk, et al., Khim.-Farm. Zh., 24(2), 139–140 (1990).
B. D. Grishchuk, P. M. Gorbovyi, and V. S. Baranovskyi, Int. Conf. “New technologies of isolation and application of biologically active substances”, Alushta (Ukraine) (2002), p. 19.
V. S. Baranovskii, G. M. Tulaidan, R. V. Simchak, et al., Nauk. Zap. Ternopil. Ped. Univ., Ser. Khim., 9, 25–28 (2005).
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 41, No. 11, pp. 27–28, November, 2007.
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Grishchuk, B.D., Klimnyuk, S.I., Simchak, R.V. et al. Synthesis and antibacterial and antifungal activity of 2-thiocyanato-2-methyl-3-arylpropionic acid allyl esters. Pharm Chem J 41, 594–595 (2007). https://doi.org/10.1007/s11094-008-0026-9
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DOI: https://doi.org/10.1007/s11094-008-0026-9