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Chemical composition and antioxidant properties of biologically active compounds from Euphrasia brevipila


Fractions of biologically active substances, including polysaccharides, iridoids, phenolic acids, and flavonoids, have been isolated from eyebright (Euphrasia brevipila) plants (Scrophulariaceae family) by chromatography on a polyamide sorbent. The following compounds were identified: aucubin; chlorogenic, ferulic, and caffeic acids; apigenin; luteolin; diosmetin; cinaroside; and cosmosiin. The antioxidant activity of the isolated biologically active substances was assessed on the model of lanolin autooxidation at 70°C in comparison to butyloxytoluene. The maximum antioxidant activity was observed for the fraction of phenolic acids that produced a fourfold increase in the stability of lanolin with respect to oxidation.

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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 6, pp. 22–26, June, 2006.

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Petrichenko, V.M., Sukhinina, T.V., Babiyan, L.K. et al. Chemical composition and antioxidant properties of biologically active compounds from Euphrasia brevipila . Pharm Chem J 40, 312–316 (2006).

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  • Flavonoid
  • Luteolin
  • Apigenin
  • Lanolin
  • Catalpol