Abstract
Microfluidic systems have become part of our everyday life, with surface microfluidics occupying its niche in instant diagnostics and point-of-care testing. Implementing surface microfluidics on a large scale appears to be impossible without developing or upgrading manufacturing technologies. Our paper proposes a CO2-laser microtechnology of precise fused silica surface processing. Key microfluidic elements–microchannels, input and deposition reservoirs have been designed, fabricated and tested with picoliter volumes of fluids. Optical transmittance of the elements remains high enough to observe reactions in a microfluidic system by means of optical methods. The above research and its results would contribute to making laser microtechnologies available to a wide range of experimental and commercial users of microfluidics.
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Acknowledgements
The authors are grateful to Laser Center LLC, St. Petersburg, Russia for providing commercial laser system “C-Marker”. The authors are grateful to the Interdisciplinary Resource Center for Nanotechnology of St. Petersburg State University for the study of the surface by scanning electron microscopy.
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The study is funded by RPMA grant of School of Physics and Engineering of ITMO University.
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All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by AGB. The first draft of the manuscript was written by AGB and RAZ and all authors commented on previous versions of the manuscript. Methodology was suggested by RAZ. Visualisation was prepared by AR-V. The study of the surface by scanning electron microscopy was performed by AVS. All authors read and approved the final manuscript. Supervision: RAZ.
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Bondarenko, A.G., Ramos-Velazquez, A., Shmalko, A.V. et al. Surface microfluidics elements fabrication by CO2-laser writing on glass: challenges and perspectives. Opt Quant Electron 55, 379 (2023). https://doi.org/10.1007/s11082-023-04675-2
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DOI: https://doi.org/10.1007/s11082-023-04675-2