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Titanium dioxide, black phosphorus and bimetallic layer-based surface plasmon biosensor for formalin detection: numerical analysis

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Abstract

Formalin detection is a deep concern in food items as its recurring consumption causes some life-taking diseases like chronic cancer. This article proposes a biosensor based on surface plasmon resonance (SPR) that uses this resonance-based concept for formalin detection. Our proposed hybrid design consists of two metallic layers of gold (Au), black phosphorus (BP) as a basic recognition element (BRE), and a single titanium dioxide layer (TiO2) film. The performance parameters were being calculated. The highest sensitivity achieved is \(327.6{\text{ deg}}/{\text{RIU}}\) for Bi-films of TiO2 and one BP film. By using attenuated total reflection (ATR), the formalin detection using biosensor with the help of reflectance and incident angle plot for various formalin concentrations. Finally, the previous and this comparative research analysis is being studied. The analysis of the proposed sensor has been carried out using COMSOL Multiphysics.

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BK formulated the problem statement, giving the theoretical background and mathematical modeling for the SPR biosensor. He also helped in drafting and finalizing the manuscript. RKC provided the theoretical background to biosensing and the importance of Optical Biosensing. He also helped in finalizing the design of the proposed sensor. SDRS worked towards the complete manuscript, formatting, and finalizing the manuscript. VS provided statistical analysis for the results. He provided the theoretical background to SPR biosensors. He also helped in formatting the manuscript. AP worked towards revising the manuscript and formatting design and finalization towards developing this work.

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Correspondence to Bhishma Karki.

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Not applicable. The work presented in this manuscript is mathematical modeling only for the proposed biosensor. No experiment was performed on the human body and living organism/ animal. So, ethical approval from an ethical committee is not required.

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Karki, B., Ramya, K.C., Sandhya Devi, R.S. et al. Titanium dioxide, black phosphorus and bimetallic layer-based surface plasmon biosensor for formalin detection: numerical analysis. Opt Quant Electron 54, 451 (2022). https://doi.org/10.1007/s11082-022-03875-6

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  • DOI: https://doi.org/10.1007/s11082-022-03875-6

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