Abstract
Time resolved inclusion investigation method has been tested based on the Monte Carlo Modeling of Light (MCML) Transport. Seven layers head structure has been built. Tissue layers are hair 100 µm, epidermis 100 µm, dermis 1 mm, skull 5 mm, cerebrospinal fluid 5 mm, gray matter 5 mm, and up to 3 cm overly thick white matter. MCML photon fluencies have been used to generate time resolved input angle forward model sensitivity weight matrix. Forward model weight matrix has been built according to the back reflected diffuse optical tomography (DOT) device model geometry. The new, triangulated input angle photon penetration model which is correlated to time resolved mode for continuous wave light has been used first. 1 source and 299 detectors were placed on the 3 cm by 3 cm grid model. Number of z Nz, and number of x Nx grid coordinates are 299 by 299. This work was done to prepare for Programmable Delay Chip (PDC) circuit included analog current input digital voltage output analog to digital converter (ADC) chip. By the help of PDC circuit, continuous wave (CW) photons which cross from different depth layers will be collected in different integrating time intervals by the capability of PDC circuit. In the simulation model, blood inclusion was buried into skull in approximately 1.8 mm depth. As long as employing the measurement capability of PDC circuit, different depth level voxels would be scanned. In this work, with the presumable existence of PDC data, an image reconstruction algorithm has been developed. The inverse problem solution has been done by pseudoinverse matrix solution method. Forward model sensitivity weight matrix functions have been calculated and used in image reconstruction algorithm.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kazanci, H.O.: Weight matrix analysis for back reflection continuous wave diffuse optical tomography (CWDOT) systems: translational method. Opt. Quantum Electron. 47(12), 3847–3853 (2015a)
Kazanci, H.O.: Designing intact clinical head laser tomography system. In: Proceedings of the IEEE Medical Technologies National Conference (TIPTEKNO). 2015 October 15–18, Bodrum, Mugla, Turkey, pp. 280–283. IEEE (2015b). https://doi.org/10.1109/tiptekno.2015.7374104
Kazanci, H.O.: Development of coordinate definition algorithm for head laser tomography system. In: Proceedings of the IEEE Medical Technologies National Conference (TIPTEKNO). 2015 October 15–18, Bodrum, Mugla, Turkey, pp. 276–279. IEEE (2015c). https://doi.org/10.1109/tiptekno.2015.7374104
Kazanci, H.O.: Non-contact head laser tomography. Opt. Quantum Electron. 48(1–7), 330 (2016a)
Kazanci, H.O.: Head model weight functions generation for laser tomography. Opt. Quantum Electron. 48(1–8), 248 (2016b)
Kazanci, H.O.: Forward model for cranial laser tomography system. Opt. Quantum Electron. 48(1–9), 395 (2016c)
Kazanci, H.O., Canpolat, M.: Mathematical method for diffuse optical tomography imaging: a research study. El-Cezerî J. Sci. Eng. 1(3), 40–48 (2014)
Kazanci, H.O., Canpolat, M.: Depth normalization algorithm for continuous wave reflectance diffuse optical tomography system. El-Cezerî J. Sci. Eng. 2(1), 40–46 (2015a)
Kazanci, H.O., Canpolat, M.: Continuous wave diffuse optical tomography system with high resolution current to voltage analog digital converter. El-Cezerî J. Sci. Eng. 2(1), 68–77 (2015b)
Kazanci, H.O., Jacques, S.L.: Diffuse light tomography to detect blood vessels using Tikhonov regularization. In: Proceedings of the SPIE—Saratov Fall Meetings SFM’15, Optical Technologies in Biophysics & Medicine XVIII; 2015 September 21–25. Saratov State University, Saratov (2015)
Kazanci, H.O., Oduncuoglu, M.: Analysis of lung tissue by laser tomography. El Cezeri J. Sci. Eng. 2(3), 75–81 (2015)
Kazanci, H.O., Mercan, T., Canpolat, M.: Design and evaluation of a reflectance diffuse optical tomography system. Opt. Quantum Electron. 47(2), 257–265 (2015)
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The author declares that he has no competing interests. Financial competing interests: In the past 5 years the author has not received reimbursements, fees, funding, or salary from any organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future. The author works as Assistant Prof. Dr. at a university that is not financing this manuscript (including the article-processing charge). The author has not held any stocks or shares in an organization that may in any way gain or lose financially from the publication of this manuscript, either now or in the future. The author does not hold or he is not currently applying for any patents relating to the content of the manuscript. The author has not received reimbursements, fees, funding, or salary from an organization that holds or has applied for patents relating to the content of the manuscript. He does not have any other financial competing interests. Non-Financial competing interests: There are no non-financial competing interests (political, personal, religious, ideological, academic, intellectual, commercial or any other) to declare in relation to this manuscript.
Rights and permissions
About this article
Cite this article
Kazanci, H.O. Time resolved inclusion investigation for continuous wave light. Opt Quant Electron 50, 137 (2018). https://doi.org/10.1007/s11082-018-1396-1
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s11082-018-1396-1