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Cognitive Sequelae of Blast-Induced Traumatic Brain Injury: Recovery and Rehabilitation

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Abstract

Blast-related traumatic brain injury (bTBI) poses a significant concern for military personnel engaged in Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF). Given the highly stressful context in which such injury occurs, psychiatric comorbidities are common. This paper provides an overview of mild bTBI and discusses the cognitive sequelae and course of recovery typical of mild TBI (mTBI). Complicating factors that arise in the context of co-morbid posttraumatic stress disorder (PTSD) are considered with regard to diagnosis and treatment. Relatively few studies have evaluated the efficacy of cognitive rehabilitation in civilian mTBI, but we discuss cognitive training approaches that hold promise for addressing mild impairments in executive function and memory, akin to those seen in OEF/OIF veterans with bTBI and PTSD. Further research is needed to address the patient and environmental characteristics associated with optimal treatment outcome.

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Acknowledgments

This research was supported by the Clinical Science Research and Development and the Rehabilitation Research and Development Services of the Department of Veterans Affairs; the National Institutes of Health and Boston University Clinical and Translational Science Institute. We thank Dr. Jennifer J. Vasterling for her expert advice and helpful discussion, and Sarah M. Kark, B.S., for assistance with manuscript preparation. The authors have no conflicts of interest to disclose.

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Bogdanova, Y., Verfaellie, M. Cognitive Sequelae of Blast-Induced Traumatic Brain Injury: Recovery and Rehabilitation. Neuropsychol Rev 22, 4–20 (2012). https://doi.org/10.1007/s11065-012-9192-3

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