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The Role of Cognitive Control in Cocaine Dependence

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Abstract

While hedonic and reward-related processes are central to drug use and dependence, this article focuses on the contribution that cognitive processes may make to addiction. In particular, attention is drawn to those processes involved in exercising control over behavior as drug dependence is characterized by risky, impulsive behavior. Functional neuroimaging implicates prefrontal deficits in cocaine dependence with an emerging picture of cocaine users having attentional biases towards drug-related stimuli, poor performance in laboratory tests of inhibitory control, and compromised monitoring and evaluation of their behavior. Combined, these deficits may contribute to the continuation of use in dependent individuals and may qualify as important targets for therapeutic interventions.

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  1. School of Psychology and Trinity College Institute of Neuroscience, Trinity College Dublin, Dublin 2, Ireland

    Hugh Garavan

  2. Trinity College Institute of Neuroscience, 3.48 Lloyd Building, Trinity College, Dublin 2, Ireland

    Hugh Garavan

  3. Queensland Brain Institute and School of Psychology, University of Queensland, St Lucia, Queensland, 4072, Australia

    Robert Hester

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Correspondence to Hugh Garavan.

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Garavan, H., Hester, R. The Role of Cognitive Control in Cocaine Dependence. Neuropsychol Rev 17, 337–345 (2007). https://doi.org/10.1007/s11065-007-9034-x

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