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Minireview: Expression and Function of Golli Protein in Immune System

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Abstract

In this minireview, the author briefly reviews the development of our understanding on the immunological function of golli proteins. In the immune system, in addition to serving as autoantigens, golli proteins have been recently found to regulate T-cell activation directly, thus modulating EAE induction. The evidence that golli proteins function as signal molecules is summarized.

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Acknowledgment

This work was supported by research grants to J.M.F from the National Multiple Sclerosis Society. The author is very grateful and indebted to Tony and Celia for leading me into my scientific career. Their encouragement, wise guidance, strength and inspiration are always with me. Tony and Celia, no words can express my thanks to you, you are my mentors forever.

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Authors and Affiliations

  1. Semel Institute of Neuroscience, UCLA Geffen School of Medicine, Neuroscience Research Building Room 304, 635 Charles Young Drive, Los Angeles, CA, 90095-7332, USA

    Ji-Ming Feng

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  1. Ji-Ming Feng
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Correspondence to Ji-Ming Feng.

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Special issue dedicated to Dr. Anthony T. Campagnoni and Celia W. Campagnoni.

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Feng, JM. Minireview: Expression and Function of Golli Protein in Immune System. Neurochem Res 32, 273–278 (2007). https://doi.org/10.1007/s11064-006-9164-1

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  • DOI: https://doi.org/10.1007/s11064-006-9164-1

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