Estimation of age and gender peculiarities of heart rate variability (HRV) in adolescents will help researchers to predict the potential abilities of the adaptation mechanisms, to evaluate the risk of cardiovascular diseases, and to select the dosage of physical activity in sporting and rehabilitation in this population. The respective data may improve our understanding of the age and sex characteristics of the autonomic nervous system during the puberty period of ontogenesis. We examined an extensive sampling (n = 812) of 12- and 13-year-old schoolchildren of both sexes. Estimation of the HRV parameters was based on the results of 5-min-long recording of electrocardiogram; generally accepted standards for the respective calculations were used. The predominance of parasympathetic regulatory influences on HRV (reflected in the RMSSD, pNN50, and HF values) was found in 12-year-old boys compared to 13-year boys and 12-year girls (P < 0.05). Among the examined girls, the predominance of parasympathetic regulation (reflected in %HF) in the HR modulation was observed in 12-year-old ones (P < 0.05), while the predominance of sympathetic regulation (%VLF) was noticeable in 13-yearold girls (P < 0.05). Thus, younger (12-year) boys are characterized by a lower tension in the central regulatory mechanisms affecting the cardiovascular system, as compared with that in older (13-year) boys and girls of both examined ages. Considering the existence of noticeable controversies between the respective data of different authors and the necessity to obtain the corresponding normative values, further studies of the dynamics of the HRV parameters in more strictly limited age and gender groups of children and adolescents are expedient.
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References
V. M. Mykhailov, Heart Rate Variability. Experience in the Practical Application of the Method [in Russian], Ivanovo (2000).
G. Seifert, G. Calaminus, A. Wiener, and D. Cysarz, “Heart rate variability reflects the natural history of physiological development in healthy children and is not associated with quality of life,” PLoS One, 9, No. 3, e91036 (2014); https://doi.org/10.1371/journal.pone.0091036.
T. G. M. Vrijkotte, B. J. H. van den Born, C. M. C. A. Ho-ekstra, et al., “Cardiac autonomic nervous system activation and metabolic profile in young children: the ABCD study,” PLoS one, 10, No. 9, e0138302 (2015); https://doi.org/10.1371/journal.pone.0138302.
Y. Zhou, G. Xie, J. Wang, and S. Yang, “Cardiovascular risk factors significantly correlate with autonomic nervous system activity in children,” Can. J. Cardiol., 28, No. 4, 477–482 (2012); https://doi.org/10.1016/j.cjca.2012.02.003.
K. L. Rennie, H. Hemingway, M. Kumari, et al., “Effects of moderate and vigorous physical activity on heart rate variability in a British study of civil servants,” Am. J. Epidemiol., 158, No. 2, 135–143 (2003); https://doi.org/10.1093/aje/kwg120.
V. K. Sharma, S. K. Subramanian, V. Arunachalam, and R. Rajendran, “Heart rate variability in adolescents–normative data stratified by sex and physical activity,” J. Clin. Diagn. Res., 9, No. 10, CC08–СС13 (2015); https://doi.org/10.7860/JCDR/2015/15373.6662.
A. Veijalainen, E. A. Haapala, J. Väistö, et al., “Associations of physical activity, sedentary time, and cardiorespiratory fitness with heart rate variability in 6-to 9-year-old children: the PANIC study,” Eur. J. Appl. Physiol., 119, Nos. 11–12, 2487–2498 (2019); https://doi.org/10.1007/s00421-019-04231-5.
A. M. Sheveleva, “Age and sex characteristics of heart rate variability in healthy adolescents,” Vestn. Volgograd State Med. Univ., 1, No. 69, 125–127 (2019); https://doi.org/10.19163/1994-9480-2019-1(69)-125-127.
R. L. Goldsmith, J. T. Bigger Jr., D. M. Bloomfield, and R. C. Steinman, “Physical fitness as a determinant of vagal modulation,” Med. Sci. Sports Exerc., 29, No. 6, 812–817 (1997).
N. Michels, E. Clays, M. De Buyzere, et al., “Determinants and reference values of short-term heart rate variability in children,” Eur. J. Appl. Physiol., 113, No. 6, 1477–1488 (2013); https://doi.org/10.1007/s00421-012-2572-9.
T. Radtke, K. Khattab, N. Brugger, et al., “High-volume sports club participation and autonomic nervous system activity in children,” Eur. J. Clin. Invest., 43, No. 8, 821–828 (2013); https://doi.org/10.1111/eci.12112.
R. S. Oliveira, A. R. Barker, and C. A. Williams, “Cardiac autonomic function, cardiovascular risk and physical activity in adolescents,” Int. J. Sports Med., 39, No. 2, 89–96 (2018); https://doi.org/10.1055/s-0043-118850.
N. Michels, I. Sioen, E. Clays, et al., “Children’s heart rate variability as stress indicator: Association with reported stress and cortisol,” Biol. Psychol., 94, No. 2, 433–440 (2013); https://doi.org/10.1016/j.biopsycho.2013.08.005.
J. Koenig, J. A. Rash, T. S. Campbell, et al., “A metaanalysis on sex differences in resting-state vagal activity in children and adolescents,” Front. Physiol., 8, 582 (2017); https://doi.org/10.3389/fphys.2017.00582.
A. M. Sitovskyi, “Teenagers physical hardworking in conditions of differential physical training with taking into consideration their biological ripening tempos,” Phys. Educ. Sport Healt. Cult. Mod. Soc., 1, No. 5, 61–65 (2009).
A. M. Sitovskyii, “Physiological measure of a differentiated approach to education of physical abilities of the girls 12–13 years,” Pedag. Psychol. Med. Biol. Probl. Phys. Train. Sport, 15, 118–123 (2004).
V. Chyzhyk and A. Sitovsky, “Evaluation of the biological age of girls on the level of development of secondary sex characteristics,” Young Sports Sci. Ukr., 2, 63–67 (2003).
N. V. Maksumova, “Assessment of vegetative tone and level of adaptation based on a comprehensive analysis of heart rate variability indicators,” Pract. Med., 3–1 Nos. 88, 46–51 (2015).
E. A. Kaliuzhnyi, S. V. Mykhailova, Yu. H. Kuzmychov, et al., “Evaluation tables of indicators of cardiointervalography of children and adolescents,” Vestn. Yakovlev Chuvash. State Pedag. Univ., 4–1, 22–25 (2011).
S. Seppälä, T. Laitinen, M. P. Tarvainen, et al., “Normal values for heart rate variability parameters in children 6–8 years of age: the PANIC Study,” Clin. Physiol. Funct. Imaging, 34, No. 4, 290–296 (2014); https://doi.org/10.1111/cpf.12096.
I. I. Makarova, I. V. Struchkova, S. M. Kushnyr, et al., “The state of heart rate variability in healthy adolescents,” Vestn. TvSU. Ser. Biol. Ecol., 24, No. 32, 37–43 (2011).
S. Moodithaya and S. T. Avadhany, “Gender differences in age-related changes in cardiac autonomic nervous function,” J. Aging Res., 2012, 679345 (2012); https://doi.org/10.1155/2012/679345.
F. M. Vanderlei, R. C. Rossi, N. M. de Souza, et al., “Heart rate variability in healthy adolescents at rest,” J. Hum. Growth Dev., 22, No. 2, 173–178 (2012).
“Heart rate variability. standards of measurements, physiological interpretation, and clinical use. Task Force of the European of Cardiology and the North American Society of Pacing and Electrophysiology,” Circulation, 93, No. 5, 1043–1065 (1996).
S. Hlants, Biomedical Statistics [in Russian], Moscow (1999).
J. S. Gąsior, J. Sacha, P. J. Jeleń, et al., “Interaction between heart rate variability and heart rate in pediatric population,” Front. Physiol., 6, 385 (2015); https://doi.org/10.3389/fphys.2015.00385.
A. R. Haleev, L. N. Yhysheva, and E. M. Kazin, “Heart rate variability in healthy children at the age of 6–16 years,” Vestn. Karazin Kharkiv Natl. Univ., 3, No. 545, 35–40 (2002).
L. A. Mykhailova, “Heart rate variability in adolescents with various types of autonomic reactivity,” Speransky Pediatr. J., 94, No. 2, 27–30 (2015).
A. Sitovskyi, B. Maksymchuk, V. Kuzmenko, et al., “Differentiated approach to physical education of adolescents with different speed of biological development,” JPES, 19, No. 3, 1532–1543 (2019); https://doi.org/10.7752/jpes.2019.03222.
A. M. Sitovskyi and V. V. Chyzhyk, “Physical preparedness of dynamics of teenagers during studying year of their biological ripening tempos,” Pedag. Psychol. Med. Biol. Probl. Phys. Train. Sport, 6, 135–140 (2009).
A. M. Sitovskyi, “Physical development of adolescents depends on their rate of biological maturation,” Pedag. Psychol. Med. Biol. Probl. Phys. Train. Sport, 12, 135–139 (2010).
M. S. Tenan, R. M. Brothers, A. J. Tweedell, et al., “Changes in resting heart rate variability across the menstrual cycle,” Psychophysiology, 51, No. 10, 996–1004 (2014); https://doi.org/10.1111/psyp.12250.
M. M. Martel, “Sexual selection and sex differences in the prevalence of childhood externalizing and adolescent internalizing disorders,” Psychol. Bull., 139, No. 6, 1221–1259 (2013); https://doi.org/10.1037/a0032247.
L. B. Sherar, D. W. Esliger, A. D. G. Baxter-Jones, and M. S. Tremblay, “Age and gender differences in youth physical activity: does physical maturity matter?,” Med. Sci. Sports Exerc., 39, No. 5, 830–835 (2007); https://doi.org/10.1249/mss.0b013e3180335c3c.
A. H. Kemp and D. S. Quintana, “The relationship between mental and physical health: insights from the study of heart rate variability,” Int. J. Psychophysiol., 89, No. 3, 288–296 (2013); https://doi.org/10.1016/j.ijpsycho.2013.06.018
T. Teisala, S. Mutikainen, A. Tolvanen, et al., “Associations of physical activity, fitness, and body composition with heart rate variability-based indicators of stress and recovery on workdays: a cross-sectional study,” J. Occup. Med. Toxicol., 9, No. 1, 16 (2014); https://doi.org/10.1186/1745-6673-9-16.
S. U. Cayres, L. C. M. Vanderlei, A. M. Rodrigues, et al., “Sports practice is related to parasympathetic activity in adolescents,” Rev. Paul. Pediatr., 33, No. 2, 174–180 (2015); https://doi.org/10.1016/j.rpped.2014.09.002.
D. J. Harriss, A. MacSween, and G. Atkinson, “Ethical standards in sport and exercise science research: 2020 update,” Int. J. Sports Med., 40, No. 13, 813–817 (2019); https://doi.org/10.1055/a-1015-3123.
World Medical Association, “World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects,” JAMA, 310, No. 20, 2191–2194 (2013); https://doi.org/10.1001/jama.2013.281053.
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Sitovskyi, A.M., Radchenko, O.V., Dmytruk, V.S. et al. Heart Rate Variability in 12- to 13-Year-Old Adolescents. Neurophysiology 52, 279–288 (2020). https://doi.org/10.1007/s11062-021-09883-8
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DOI: https://doi.org/10.1007/s11062-021-09883-8