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Electrical Activity of the Cerebral Structures and Regulatory Effects of NO, Steroid Hormones, and BDNF in Rats with Experimental Alcohol Addiction

  • PROCEEDINGS OF THE VII CONGRESS OF THE UKRAINIAN NEUROSCIENCE SOCIETY (Kyiv, June 7-11, 2017)
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Neurophysiology Aims and scope

In a chronic experiment on rats with induced alcohol addiction, it was shown that chronic alcoholization leads to decreases in the levels of cortisol and testosterone in the hypothalamus, amygdalar complex, and blood serum. Functional changes in the hippocampus and nucl. accumbens are believed to play a leading role in the formation of the alcohol withdrawal syndrome. Under these conditions, the level of NO metabolites in the above structures decreases against the background of increased BDNF concentrations in blood serum.

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References

  1. I. P. Anokhina, N. L. Vekshina, and A. G. Veretinskaya, “Central mechanisms of predisposition to the dependence on psychoactive agents,”Korsakov Zh. Neurol. Psikhiatr., 12, 83-86 (1997).

    Google Scholar 

  2. T. M. Vorob’yova, “Neurobiology of secondary acquired motivations,” Mezhdunar. Med. Zh., Nos. 1/2, 211-217 (2002).

  3. J. Bures, M. Petran, and I. Zachar, Electrophysiological Methods in Biological Research, Publ. House Foreign Lit., Moscow (1962).

    Google Scholar 

  4. P. P. Golikov and N. Yu. Nikolayeva, “Methods of measurement of nitric oxide (NOx) in the cerebrospinal liquid of neurosurgical patients,” Neirokhirurgiya, No. 3, 35-37 (2003).

    Google Scholar 

  5. R. Ward, “Biochemical and neurotransmitter changes implicated in alcohol-induced brain damage in chronic or ‘binge drinking’ alcohol abuse,” Alcohol Alcohol, 44, No. 2, 128-135 (2009).

    Article  CAS  PubMed  Google Scholar 

  6. E. P. Hayden, R. E. Wiegand, E. T. Meyer, et al., “Patterns of regional brain activity in alcohol-dependent subjects,” Alcoholism: Clin. Exp. Res., 30, No. 12, 1986-1991 (2006).

    Article  Google Scholar 

  7. P. Coutin-Сhurchman and R. Moreno, “Intracranial current density (LORETA) differences in QEEG frequency bands between depressed and non-depressed alcoholic patients,” Clin. Neurophysiol., 119, No. 4, 948-958 (2008).

    Article  Google Scholar 

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Authors and Affiliations

  1. Institute of Neurology, Psychiatry, and Narcology, NAMS of Ukraine, Kharkiv, Ukraine

    O. G. Berchenko, A. M. Titkova, O. V. Veselovs’ka, A. V. Shlyakhova, N. O. Levicheva & O. O. Prikhod’ko

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  1. O. G. Berchenko
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  2. A. M. Titkova
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  3. O. V. Veselovs’ka
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  4. A. V. Shlyakhova
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  5. N. O. Levicheva
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  6. O. O. Prikhod’ko
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Correspondence to O. G. Berchenko.

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Berchenko, O.G., Titkova, A.M., Veselovs’ka, O.V. et al. Electrical Activity of the Cerebral Structures and Regulatory Effects of NO, Steroid Hormones, and BDNF in Rats with Experimental Alcohol Addiction. Neurophysiology 49, 234–236 (2017). https://doi.org/10.1007/s11062-017-9668-0

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  • DOI: https://doi.org/10.1007/s11062-017-9668-0

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