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NADPH-Diaphorase reactivity and neurovascular coupling in the basal forebrain and motor cortex

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Using NADPH-diaphorase histochemistry, distribution of reactive neurons in the forebrain structures and motor cortex of rats was studied. Some reactive (NO-generating) neurons are associated with microvessels and, thus, can be involved in the regulation of regional blood flow.

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References

  1. J. Marino and J. Cudeiro, “How does the brain wake up? The nitric oxide blow,” Rev. Neurol., 42, 535–541 (2006).

    PubMed  CAS  Google Scholar 

  2. Q. Gu, “Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity,” Neuroscience, 111, 815–835 (2002).

    Article  PubMed  CAS  Google Scholar 

  3. X. K. Tong and E. Hamel, “Basal forebrain nitric oxide synthase (NOS)-containing neurons project to microvessels and NOS neurons in the rat neocortex: cellular basis for cortical blood flow regulation,” Eur. J. Neurosci., 12, 2769–2780 (2000).

    Article  PubMed  CAS  Google Scholar 

  4. E. Hamel, “Cholinergic modulation of the cortical microvascular bed,” Prog. Brain Res., 145, 171–178 (2004).

    Article  PubMed  CAS  Google Scholar 

  5. E. Hamel, “Perivascular nerves and the regulation of cerebro-vascular tone,” J. Appl. Physiol., 100, 1059–1064 (2006).

    Article  PubMed  Google Scholar 

  6. E. Vaucher and E. Hamel, “Cholinergic basal forebrain neurons project to cortical microvessels in the rat: electron microscopic study with anterogradely transported Phaseolus vulgaris leucoagglutinin and choline acetyltransferase immunocytochemistry,” J. Neurosci., 15, 7427–7441 (1995).

    PubMed  CAS  Google Scholar 

  7. B. Cauli, X. K. Tong, A. Rancillac, et al., “Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways,” J. Neurosci., 24, 8940–8949 (2004).

    Article  PubMed  CAS  Google Scholar 

  8. A. I. Pilyavskii, O. V. Vlasenko, A. V. Maznychenko, and V. A. Maisky, “Expression of c-fos in the islands of Calleja and adjoining centers of the brain following fatiguing stimulation of the dorsal neck muscles in the rat,” Russ. J. Neurosci., 2, 8–14 (2007).

    Google Scholar 

  9. M. M. Mesulam, E. J. Mufson, B. H. Wainer, and A. I. Levey, “Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6),” Neuroscience, 10, 1185–1201 (1983).

    Article  PubMed  CAS  Google Scholar 

  10. X. K. Tong and E. Hamel, “Regional cholinergic denervation of cortical microvessels and nitric oxide synthase-containing neurons in Alzheimer’s disease,” Neuroscience, 92, 163–75 (1999).

    Article  PubMed  CAS  Google Scholar 

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Correspondence to V. A. Maisky.

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Neirofiziologiya/Neurophysiology, Vol. 39, Nos. 4/5, pp. 405–407, July–October, 2007.

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Vlasenko, O.V., Dovgan’, A.V., Maisky, V.A. et al. NADPH-Diaphorase reactivity and neurovascular coupling in the basal forebrain and motor cortex. Neurophysiology 39, 355–357 (2007). https://doi.org/10.1007/s11062-007-0056-z

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  • DOI: https://doi.org/10.1007/s11062-007-0056-z

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