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Involvement of L-type calcium channels and mitochondria in post-tetanic potentiation: Is it a general rule for different types of synapses?

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Neurophysiology Aims and scope

Abstract

Our experiments and studies of a few other authors demonstrated that L-type calcium channels and mitochondria are involved in the induction of post-tetanic potentiation (PTP) in a number of preparations (Aplysia central nervous system, hippocampal cell cultures, crayfish neuromuscular junctions, etc.). We extend this conclusion on cortical synapses by the demonstration that inhibitors of mitochondrial Ca2+ uptake and release suppress PTP in rat neocortical cell cultures.

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Authors and Affiliations

  1. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine

    M. V. Storozhuk, S. Yu. Ivanova & P. G. Kostyuk

  2. International Center of Molecular Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine

    M. V. Storozhuk, S. Yu. Ivanova & P. G. Kostyuk

  3. Meharry Medical College, Nashville, USA

    S. M. Fredman

  4. Institute of Higher Nervous Activity and Neurophysiology, Moscow, Russia

    P. M. Balaban

Authors
  1. M. V. Storozhuk
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  2. S. M. Fredman
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  3. S. Yu. Ivanova
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  4. P. M. Balaban
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  5. P. G. Kostyuk
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Corresponding author

Correspondence to M. V. Storozhuk.

Additional information

Neirofiziologiya/Neurophysiology, Vol. 39, Nos. 4/5, pp. 403–404, July–October, 2007.

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Storozhuk, M.V., Fredman, S.M., Ivanova, S.Y. et al. Involvement of L-type calcium channels and mitochondria in post-tetanic potentiation: Is it a general rule for different types of synapses?. Neurophysiology 39, 353–354 (2007). https://doi.org/10.1007/s11062-007-0055-0

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  • DOI: https://doi.org/10.1007/s11062-007-0055-0

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