Skip to main content
SpringerLink
Log in

RETRACTED ARTICLE:Contribution of GABAA receptor-mediated inhibition to the determination of the velocity tuning of low pass-tuned neurons of the Superior Colliculus

  • Published:
Neurophysiology Aims and scope

This article was retracted on 15 March 2019

Abstract

The participation of intrinsic inhibitory networks in providing the velocity selectivity of neurons of the superior colliculus (SC) of the Syrian hamster was tested using iontophoretic application of bicuculline methiodide, a GABAA receptor competitive antagonist. The impulse activity of 22 low pass-tuned (LP) cells was recorded extracellularly. Following application of bicuculline, 10 cells exhibited an increase in the velocity selectivity, while the other 12 units showed decreases in their tuning. We assume that SC intrinsic inhibitory networks contributing to the velocity tuning of neurons of this structure are driven in a dissimilar way by afferent volleys arriving from the retina through “fast” Y and “slow” W channels.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. W. Goodwin and G. H. Henry, “The influence of stimulus velocity on the responses of single neurones in the striate cortex,” J. Physiol., 277, 467–482 (1978).

    Article  CAS  Google Scholar 

  2. J. Liu and W. T. Newsome, “Correlation between speed perception and neural activity in the middle temporal visual area,” J. Neurosci., 25, No. 3, 711–722 (2005).

    Article  CAS  Google Scholar 

  3. W. J. Waleszczyk, C. Wang, W. Burke, and B. Dreher, “Velocity response profiles of collicular neurons: parallel and convergent visual information channels,” Neuroscience, 93, No. 3, 1063–1076 (1999).

    Article  CAS  Google Scholar 

  4. A. B. Bonds, “Role of inhibition in the specification of orientation selectivity of cells in the cat striate cortex,” Vis. Neurosci., 2, No. 1, 41–55 (1989).

    Article  CAS  Google Scholar 

  5. N. J. Priebe and D. Ferster, “Direction selectivity of excitation and inhibition in simple cells of the cat primary visual cortex,” Neuron, 45, No. 1, 133–145 (2005).

    Article  CAS  Google Scholar 

  6. A. M. Sillito, “The effectiveness of bicuculline as an antagonist of GABA and visually evoked inhibition in the cat’s striate cortex,” J. Physiol., 250, No. 2, 287–304 (1975).

    Article  CAS  Google Scholar 

  7. D. M. Berson, “Retinal W-cell input to the upper superficial gray layer of the cat’s superior colliculus: a conduction-velocity analysis,” J. Neurophysiol., 58, No. 5, 1035–1051 (1987).

    Article  CAS  Google Scholar 

  8. R. D. Mooney and R. W. Rhoades, “Relationships between physiological and morphological properties of retinocollicular axons in the hamster,” J. Neurosci., 10, No. 9, 3164–3177 (1990).

    Article  CAS  Google Scholar 

  9. Y. Fukuda and J. Stone, “Evidence of differential inhibitory influences on X-and Y-type relay cells in the cat’s lateral geniculate nucleus,” Brain Res., 113, No. 1, 188–196 (1976).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Georgia State University, Atlanta, Georgia, USA

    V. I. Khorevin

  2. Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine

    V. I. Khorevin

Authors
  1. V. I. Khorevin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. I. Khorevin.

Additional information

Neirofiziologiya/Neurophysiology, Vol. 39, Nos. 4/5, pp. 385–387, July–October, 2007.

This article has been retracted by the Editor in Chief because it was published without agreement of the laboratory's managers and without giving credits to the group of researchers who obtained the experimental data. The author agrees to the retraction.

An erratum to this article can be found online at https://doi.org/10.1007/s11062-019-09806-8

About this article

Cite this article

Khorevin, V.I. RETRACTED ARTICLE:Contribution of GABAA receptor-mediated inhibition to the determination of the velocity tuning of low pass-tuned neurons of the Superior Colliculus . Neurophysiology 39, 337–338 (2007). https://doi.org/10.1007/s11062-007-0049-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11062-007-0049-y

Keywords

Search

Navigation