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A novel finding of an IDH2 mutation in an interesting adult Sonic Hedgehog mutated medulloblastoma

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References

  1. Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B et al (2017) Intertumoral heterogeneity within medulloblastoma subgroups. Cancer Cell 31(6):737–754

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Kool M, Jones DT, Jäger N, Northcott PA, Pugh TJ, Hovestadt V et al (2014) Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell 25(3):393–405

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T et al (2012) Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature 488(7409):49–56

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Remke M, Ramaswamy V, Peacock J, Shih DJ, Koelsche C, Northcott PA et al (2013) TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol 126(6):917–929

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

The authors wish to acknowledge Drs. Anita Huttner, Zachary Corbin and Robert Fulbright for their contribution for their expertise and care for this patient.

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  1. Department of Neurosurgery, Yale School of Medicine, 15 York St, LLCI 810, New Haven, CT, 06520-8082, USA

    Elena I. Fomchenko, E. Zeynep Erson-Omay & Jennifer Moliterno

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  1. Elena I. Fomchenko
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  2. E. Zeynep Erson-Omay
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  3. Jennifer Moliterno
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Correspondence to Jennifer Moliterno.

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The authors report no pertinent disclosures, and no conflict of interest concerning the materials or methods used in this study, or findings described in this paper.

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Fomchenko, E.I., Erson-Omay, E.Z. & Moliterno, J. A novel finding of an IDH2 mutation in an interesting adult Sonic Hedgehog mutated medulloblastoma. J Neurooncol 144, 231–233 (2019). https://doi.org/10.1007/s11060-019-03207-x

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  • DOI: https://doi.org/10.1007/s11060-019-03207-x

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