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Journal of Neuro-Oncology

, Volume 116, Issue 1, pp 99–106 | Cite as

Surgical outcomes in spinal cord subependymomas: an institutional experience

  • Liang Wu
  • Tao Yang
  • Xiaofeng Deng
  • Chenlong Yang
  • Lei Zhao
  • Jingyi Fang
  • Guihuai Wang
  • Jun Yang
  • Yulun XuEmail author
Clinical Study

Abstract

Spinal cord subependymomas are very rare. Most studies on spinal cord subependymomas have been case reports with literature reviews. This study presented a surgical series of 13 patients with histologically proven spinal cord subependymomas. Their clinical data, radiological findings, operative records, and follow-up outcomes were reviewed. There were 5 male and 8 female patients with a mean age of 39.5 years. The mean follow-up period was 67.8 months. Four tumors were located in the cervical spine, 5 in the cervicothoracic spine, and 4 in the thoracic spine. Gross total resection (GTR) of the tumor with a well-demarcated dissection plane was achieved in 9 cases, and subtotal resection was achieved in 4 cases. The symptoms present before the surgery were improved in 11 cases at last follow-up and the current status of 2 patients had no change compared to the preoperative presentation at last follow-up. The postoperative follow-up magnetic resonance imaging showed no recurrence in the 9 GTR cases during the mean follow-up period of 70.3 months. No recurrence/regrowth of the residual tumors was observed in the 4 STR cases during the mean follow-up period of 62.0 months. Spinal cord subependymomas are amenable to surgical resection. It is possible to achieve GTR of intramedullary subependymomas that have a well-demarcated dissection plane. When GTR cannot be achieved, STR of the lesion for decompression is advised, and follow-up imaging is needed. A good clinical outcome after GTR or STR can be expected.

Keywords

Subependymoma Surgical resection Spinal cord tumor Ependymal tumor 

Notes

Acknowledgments

We would like to thank all the patients who trusted us and all the physicians and staff who helped this study.

Conflict of interest

The authors report no conflict of interest concerning the materials or methods used in this study or the findings described in this paper. No benefits in any form have been or will be received from any commercial party related directly or indirectly to the subject of this manuscript.

Ethical standards

This retrospective study was approved by Institutional Review Board of Beijing Tiantan Hospital, Capital Medical University.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Liang Wu
    • 1
  • Tao Yang
    • 1
  • Xiaofeng Deng
    • 1
  • Chenlong Yang
    • 1
  • Lei Zhao
    • 1
  • Jingyi Fang
    • 2
  • Guihuai Wang
    • 1
  • Jun Yang
    • 1
  • Yulun Xu
    • 1
    Email author
  1. 1.Department of NeurosurgeryBeijing Tiantan Hospital, Capital Medical UniversityBeijingChina
  2. 2.Department of Neuropathology, Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina

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