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Extraventricular anaplastic ependymoma with metastasis to scalp and neck

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Abstract

We report a case of anaplastic ependymoma with extracranial metastases in a 22-year-old female. The patient originally presented with headaches and dysarthria. Neuroimaging revealed a large solid and cystic right fronto-temporal lesion. It was located completely extraventricularly and a glioblastoma was suspected based on the neuroimaging findings. A gross total resection was achieved. Histopathologic examination revealed an anaplastic ependymoma. The patient was treated with radiotherapy. Approximately 1 year after the initial surgery, the patient presented with metastatic disease to the scalp. At 2 years, an intraparotid metastasis was detected. Subsequent neck dissection revealed positive lymph nodes at several levels. It was followed by radiotherapy to the neck. 5 years after the initial surgery, the patient has residual metastatic disease. The case is discussed and the literature on extraventricular ependymal neoplasms is reviewed.

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Authors and Affiliations

  1. The Ruth and Bruce Rappaport Faculty of Medicine Technion - Israel Institute of Technology, 12 Efron St., Haifa, 31096, Israel

    Matthew J. Davis

  2. Department of Pathology, University Health Network, 200 Elizabeth St., E11-444, Toronto, ON, M5G 2C4, Canada

    Ilan Weinreb & Tim-Rasmus Kiehl

  3. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

    Fauzia Hasan, Ilan Weinreb & Tim-Rasmus Kiehl

  4. The Krembil Neuroscience Centre, University Health Network, Toronto, ON, M5T 2S8, Canada

    M. Christopher Wallace

  5. Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, M5T 2S8, Canada

    M. Christopher Wallace

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  1. Matthew J. Davis
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  2. Fauzia Hasan
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  3. Ilan Weinreb
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  5. Tim-Rasmus Kiehl
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Correspondence to Tim-Rasmus Kiehl.

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Davis, M.J., Hasan, F., Weinreb, I. et al. Extraventricular anaplastic ependymoma with metastasis to scalp and neck. J Neurooncol 104, 599–604 (2011). https://doi.org/10.1007/s11060-010-0525-x

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  • DOI: https://doi.org/10.1007/s11060-010-0525-x

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