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Mixed testicular germ cell tumour in a patient with previous pineal germinoma

Journal of Neuro-Oncology volume 101, pages 125–128 (2011)Cite this article

Abstract

Germ cell tumours (GCT) are a relatively common malignancy in men aged 15–35 years. They occur most frequently in the gonads, but 3–5% have extragonadal origin, mainly in the pineal gland, neurohypophysis, mediastinum and retroperitoneum. Although intracranial germinomas may present with synchronous midline lesions, development of metachronous testicular germ cell primaries seems to be extremely rare, and confirmed dissemination of intracranial GCT to the testes has never been reported. We report the case of a 32-year-old man, with previously treated pineal germinoma at age 16 years, who later developed mixed GCT of the left testis.

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Affiliations

  1. Department of Neurology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Rua Professor Lima Basto, 1099-023, Lisbon, Portugal

    Vanessa B. Silva, Ana L. Azevedo, Ilda M. Costa & José M. Bravo-Marques

  2. Department of Pathology, Centro Hospitalar de Lisboa Central – Hospital de São José, Rua José António Serrano, 1150-199, Lisbon, Portugal

    Manuela S. Mafra

  3. Department of Medical Oncology, Instituto Português de Oncologia de Lisboa Francisco Gentil, Rua Professor Lima Basto, 1099-023, Lisbon, Portugal

    José L. Passos-Coelho

Authors
  1. Vanessa B. Silva
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  2. Ana L. Azevedo
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  3. Ilda M. Costa
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  4. Manuela S. Mafra
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  5. José L. Passos-Coelho
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  6. José M. Bravo-Marques
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Correspondence to Vanessa B. Silva.

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Silva, V.B., Azevedo, A.L., Costa, I.M. et al. Mixed testicular germ cell tumour in a patient with previous pineal germinoma. J Neurooncol 101, 125–128 (2011). https://doi.org/10.1007/s11060-010-0213-x

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  • DOI: https://doi.org/10.1007/s11060-010-0213-x

Keywords

  • Central nervous system
  • Germ cell tumour
  • Germinoma
  • Extragonadal
  • Pineal
  • Testis