Skip to main content
SpringerLink
Log in

Meningioma in untreated congenital adrenal hyperplasia: a relationship?

  • Case report
  • Published:
Journal of Neuro-Oncology Aims and scope Submit manuscript

Abstract

Steroid hormones have been implicated in the growth and/or development of meningiomas. A 46, XX male with untreated congenital adrenal hyperplasia who developed meningiomas is presented here. The meningiomas only expressed progesterone receptors, as most meningiomas do. The high 17-hydroxyprogesterone levels, resulting from his disease, could have played a role in the development and growth of his meningiomas.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Nakasu S, Hirano A, Shimura T, Llena JF (1987) Incidental meningiomas in autopsy study. Surg Neurol 27:319–322. doi:10.1016/0090-3019(87)90005-X

    Article  PubMed  CAS  Google Scholar 

  2. Kepes JJ (2008) Meningiomas: biology, pathology and differential diagnosis. Masson Publishing, U.S. New York, pp 17–19

    Google Scholar 

  3. Christensen HC, Kosteljanetz M, Johansen C (2003) Incidences of gliomas and meningiomas in Denmark, 1943–1997. Neurosurgery 52:1327–1333. doi:10.1227/01.NEU.0000064802.46759.53

    Article  PubMed  Google Scholar 

  4. Kubo M, Fukutomi T, kashi-Tanaka S, Hasegawa T (2001) Association of breast cancer with meningioma: report of a case and review of the literature. Jpn J Clin Oncol 31:510–513. doi:10.1093/jjco/hye109

    Article  PubMed  CAS  Google Scholar 

  5. Blitshteyn S, Crook JE, Jaeckle KA (2008) Is there an association between meningioma and hormone replacement therapy? J Clin Oncol 26:279–282. doi:10.1200/JCO.2007.14.2133

    Article  PubMed  CAS  Google Scholar 

  6. Roelvink NC, Kamphorst W, van Alphen HA, Rao BR (1987) Pregnancy-related primary brain and spinal tumors. Arch Neurol 44:209–215

    PubMed  CAS  Google Scholar 

  7. Strumph PS, Stechison MT, Lee PA (1995) Meningioma in congenital adrenal hyperplasia. Endocr Pract 1:161–162

    PubMed  CAS  Google Scholar 

  8. Blankenstein MA, Verheijen FM, Jacobs JM, Donker TH, van Duijnhoven MW, Thijssen JH (2000) Occurrence, regulation, and significance of progesterone receptors in human meningioma. Steroids 65:795–800. doi:10.1016/S0039-128X(00)00193-8

    Article  PubMed  CAS  Google Scholar 

  9. Bickerstaff ER, Small JM, Guest IA (1958) The relapsing course of certain meningiomas in relation to pregnancy and menstruation. J Neurol Neurosurg Psychiatry 21:89–91

    Article  PubMed  CAS  Google Scholar 

  10. Moss J, DeCastro R, Patronas NJ, Taveira-DaSilva A (2001) Meningiomas in lymphangioleiomyomatosis. JAMA 286:1879–1881. doi:10.1001/jama.286.15.1879

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Clinical Chemistry, VU University Medical Center, Amsterdam, HV, 1081, The Netherlands

    Annemieke C. Heijboer & Marinus A. Blankenstein

  2. Department of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands

    J. Coen Netelenbos

Authors
  1. Annemieke C. Heijboer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Coen Netelenbos
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marinus A. Blankenstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Annemieke C. Heijboer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Heijboer, A.C., Netelenbos, J.C. & Blankenstein, M.A. Meningioma in untreated congenital adrenal hyperplasia: a relationship?. J Neurooncol 92, 223–225 (2009). https://doi.org/10.1007/s11060-008-9751-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11060-008-9751-x

Keywords

Search

Navigation