We report the case of a 63-year-old man who developed an anaplastic oligoastrocytoma of the brain stem and midbrain 13 years after postoperative high-dose proton–photon radiation therapy for a recurrent low-grade chondrosarcoma of the skull base. To our knowledge, this is the first reported case of an anaplastic glioma after proton–photon irradiation.
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Ehsani, S., Hodaie, M., Liebsch, N.J. et al. Anaplastic glioma after high-dose proton–photon radiation treatment for low-grade skull base chondrosarcoma. J Neurooncol 88, 231–236 (2008). https://doi.org/10.1007/s11060-008-9560-2
- Anaplastic glioma
- Brain tumor
- Proton radiation therapy
- Radiation-associated tumor
- Skull base chondrosarcoma