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Glioblastoma multiforme with an abscess: case report and literature review

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Abstract

An intratumoral or peritumoral microbial intracranial abscess is an infrequent diagnosis. The development of this complication may not be preceded by apparent local or general infection in all cases. To identify this diagnosis by radiological (MRI) or laboratory investigations is very intricate. Nevertheless, the recommended life-saving strategy is early surgery with resolution of both the tumor and infection. If subsequent oncological treatment is required, it has to be adjusted for prevention of re-inflammation. The described patient suffered from an intracranial abscess superimposed on a Glioblastoma Multiforme. The confirmed etiological agent was Staphylococcus aureus. The suspected route of microbial migration and colonization in this tumor was bacteremia via agents from thrombophlebitis. The patient is in a good condition following surgery, antimicrobial treatment, and radiotherapy.

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Acknowledgements

This study was supported by grant projects of Ministry of School and Education of the Czech Republic (MSM6198959216 and LC07017).

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Authors and Affiliations

  1. Neurosurgical Department, University Hospital, I.P. Pavlova 6, Olomouc, 77520, Czech Republic

    Ondrej Kalita, Miroslav Kala & Michael Houdek

  2. Oncologic Department, University Hospital, I.P. Pavlova 6, Olomouc, 77520, Czech Republic

    Hana Svebisova

  3. Institute of Pathology, Laboratory of Molecular Pathology, Centre of Molecular Biology, University Hospital, Hnevotinska 6, Olomouc, 77515, Czech Republic

    Jiri Ehrmann & Alice Hlobilkova

  4. Laboratory of Experimental Medicine, University Hospital, Puskinova 6, Olomouc, 77520, Czech Republic

    Radek Trojanec & Marian Hajduch

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  1. Ondrej Kalita
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Correspondence to Ondrej Kalita.

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Kalita, O., Kala, M., Svebisova, H. et al. Glioblastoma multiforme with an abscess: case report and literature review. J Neurooncol 88, 221–225 (2008). https://doi.org/10.1007/s11060-008-9557-x

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  • DOI: https://doi.org/10.1007/s11060-008-9557-x

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