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CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous system

  • Clinical-Patient Studies
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Abstract

Isolated post-transplant lymphoproliferative disorder (PTLD) of the central nervous system is rare and its diagnosis can be challenging. A biopsy is usually required in order to distinguish the disease from opportunistic infections. We present a case in whom immunoglobulin heavy chain gene rearrangement analysis of cerebrospinal fluid (CSF) was instrumental in establishing the diagnosis.

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Authors and Affiliations

  1. Department of Neurology and Neurosurgery, Yale University School of Medicine, 333 Cedar Street, TMP412, New Haven, CT, 06510, USA

    Joachim M. Baehring

  2. Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA

    Marie-Louise Landry

  3. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA

    Dennis Cooper

  4. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA

    Pei Hui & Serguei Bannykh

Authors
  1. Joachim M. Baehring
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  2. Marie-Louise Landry
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  3. Dennis Cooper
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  4. Pei Hui
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  5. Serguei Bannykh
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Corresponding author

Correspondence to Joachim M. Baehring.

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Baehring, J.M., Landry, ML., Cooper, D. et al. CSF IgH gene rearrangement analysis in isolated post-transplant lymphoproliferative disorder of the central nervous system. J Neurooncol 86, 57–60 (2008). https://doi.org/10.1007/s11060-007-9429-9

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  • DOI: https://doi.org/10.1007/s11060-007-9429-9

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