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Carcinomatous Meningitis from Urachal Carcinoma: The First Reported Case

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Summary

Carcinomatous meningitis (CM) occurs in less than 10% of cancer patients. Although patients frequently present with a focal complaint, multifocal signs are often found following careful neurological examination. The gold standard for diagnosis remains the demonstration of neoplastic cells in the cerebrospinal fluid. Despite the discouraging prognosis, palliative treatment may improve quality of life and lengthen lifespan. We report a patient with known primary carcinoma of the urachus who presented with headaches, nausea, vomiting and ataxia 1 week following resection of a nodular arachnoidal metastasis (indenting the cerebellum). Lumbar cerebrospinal fluid subsequently confirmed carcinomatous meningitis. This is the first reported case of carcinomatous meningitis resulting from metastatic urachal carcinoma.

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Authors and Affiliations

  1. Department of Neurological Surgery, Neurological Institute of New York, New York, NY, USA

    Shearwood McClelland III, Rebeca E Garcia, Ty J Olson, Grace H Kim & Robert R Goodman

  2. Columbia College of Physicians and Surgeons, Department of Pathology, New York, NY, USA

    Sara E Monaco & James E Goldman

  3. Department of Medicine, Columbia College of Physicians and Surgeons, New York, NY, USA

    Daniel P Petrylak

Authors
  1. Shearwood McClelland III
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  2. Rebeca E Garcia
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  3. Sara E Monaco
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  4. James E Goldman
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  5. Ty J Olson
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  6. Grace H Kim
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  7. Daniel P Petrylak
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  8. Robert R Goodman
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Corresponding author

Correspondence to Robert R Goodman.

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McClelland, S., Garcia, R.E., Monaco, S.E. et al. Carcinomatous Meningitis from Urachal Carcinoma: The First Reported Case. J Neurooncol 76, 171–174 (2006). https://doi.org/10.1007/s11060-005-4815-7

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  • DOI: https://doi.org/10.1007/s11060-005-4815-7

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