Characteristics of Cognitive Impairments in Alcoholic and Dyscirculatory Encephalopathies

Objective. To identify the features of cognitive impairments (CI) in patients with alcoholic (AE) and dyscirculatory (DE) encephalopathies. Materials and methods. The study included 32 patients with DE and 30 with AE. Along with clinical observations, patients underwent computerized electroencephalography (EEG), recording of cognitive event-related potentials, and neuropsychological testing. Results and conclusions. The pathologies studied here showed both common and distinct signs in the clinical picture, in the emotional-personality domain, and impairments to cognitive processes. Common features of encephalopathies of different etiologies were CI and asthenic syndrome; AE was characterized by hyposthenic and DE by mixed (hyper- and hyposthenic) syndromes. The EEG showed that changes in bioelectrical activity in DE were predominantly located in the occipital-parietal areas of the cortex, while in AE they were located in the temporal and occipital-parietal areas. CI in DE and AE consisted of disorders to categorial thinking, long-term memory, reciprocal coordination, and digital gnosis, pointing to dysfunction of the frontal and parietal lobes of the left hemisphere, hippocampus, and corpus callosum. The indexes of the δ, β1, and β2 rhythms were discriminating features of CI in AE and DE.

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Correspondence to O. I. Shevchenko.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 120, No. 5, Iss. 1, pp. 16–23, May, 2020.

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Shevchenko, O.I., Lakhman, O.L. & Katamanova, E.V. Characteristics of Cognitive Impairments in Alcoholic and Dyscirculatory Encephalopathies. Neurosci Behav Physi 51, 36–41 (2021).

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  • cognitive impairments
  • alcoholic encephalopathy
  • dyscirculatory encephalopathy
  • differential diagnosis