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Reorganization of Bioelectrical Activity in the Neocortex after Stroke by Rehabilitation Using a Brain–Computer Interface Controlling a Wrist Exoskeleton

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The process of the functional rearrangement of the motor cortex of the brain after stroke is due to neuroplasticity, and this underlies motor recovery. Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are currently recognized as the most informative methods for studying these processes. The course of the neuroplastic process can be evaluated from the power levels of EEG rhythms during imagination of movements in the paralyzed arm in right-handed patients after stroke in the left hemisphere monitored at different times – before and after courses of neurorehabilitation using a brain–computer interface controlling a wrist exoskeleton. Powerful excitatory interactions in the primary motor cortex and frontoparietal areas in the lesioned and “intact” hemispheres are initially seen, and these probably reflect reorganization of neural networks. Rehabilitation courses were followed by restoration of bioelectrical activity in the primary motor cortex due to recovery of efficient connections with the premotor and superior parietal zones and decreases in the pathological influences of the contralateral hemisphere.

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Authors and Affiliations

  1. Vladimirskii Moscow Regional Research Clinical Institute, Moscow, Russia

    S. V. Kotov, M. V. Romanova, A. A. Kondur, L. G. Turbina, E. V. Isakova & E. V. Zaitseva

  2. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia

    E. V. Biryukova & A. A. Frolov

  3. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia

    E. V. Biryukova & A. A. Frolov

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  1. S. V. Kotov
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  2. M. V. Romanova
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  3. A. A. Kondur
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  4. E. V. Biryukova
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  5. A. A. Frolov
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  8. E. V. Zaitseva
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Correspondence to S. V. Kotov.

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Translated from Zhurnal Vysshei Nervnoi Deyatel’nosti imeni I. P. Pavlova, Vol. 70, No. 2, pp. 217–230, March–April, 2020.

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Kotov, S.V., Romanova, M.V., Kondur, A.A. et al. Reorganization of Bioelectrical Activity in the Neocortex after Stroke by Rehabilitation Using a Brain–Computer Interface Controlling a Wrist Exoskeleton. Neurosci Behav Physi 50, 1146–1154 (2020). https://doi.org/10.1007/s11055-020-01017-7

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