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Gait Impairments and Postural Instability in Parkinson’s Disease on the Background of Chronic Stimulation of Subcortical Structures

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The surgical treatment of patients with Parkinson’s disease (PD) has in recent years firmly fixed its place in the overall algorithm of managing patients with this pathology. The most advanced and promising method is deep brain electrical stimulation, which decreases the severity of the main clinical manifestations of the disease, including some of the axial symptoms. The time characteristics of parkinsonian gait remains resistant to treatment by stimulation of the subthalamic nucleus. Levodopa-sensitive freezing during walking can decrease on stimulation of the subthalamic nucleus. This review summarizes the effects of stimulation of subcortical structures on gait abnormalities and postural instability in PD.

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Authors and Affiliations

  1. Russian Medical Academy of Continuing Professional Training, Russian Ministry of Health, Moscow, Russia

    S. G. Sultanova, N. V. Fedorova & E. V. Bril

  2. Burdenko National Medical Research Center for Neurosurgery, Russian Ministry of Health, Moscow, Russia

    A. A. Gamaleya & A. A. Tomskiy

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  1. S. G. Sultanova
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  2. N. V. Fedorova
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  3. E. V. Bril
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Correspondence to S. G. Sultanova.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 119, No. 9, Iss. 1, pp. 123–130, September, 2019.

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Sultanova, S.G., Fedorova, N.V., Bril, E.V. et al. Gait Impairments and Postural Instability in Parkinson’s Disease on the Background of Chronic Stimulation of Subcortical Structures. Neurosci Behav Physi 50, 676–682 (2020). https://doi.org/10.1007/s11055-020-00954-7

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