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Sleep and Cognitive Impairments in Neurodegenerative Diseases

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Impairments of sleep and waking in diseases such as Parkinson’s disease, dementia, Lewy body dementia, and Alzheimer’s disease are encountered in a large proportion of patients. Sleep has many functions, supporting the normal operation of the brain, and impairments to sleep may be among the factors promoting the development of neurodegenerative diseases. Impairments to sleep and waking may exacerbate the course of the neurodegenerative process and lead to increases in symptoms, including cognitive impairments. This article presents a detailed analysis of the literature linking sleep and waking impairments and cognitive impairments in neurodegenerative diseases. The phenomenology and methods of correcting sleep and waking impairments in these diseases are discussed.

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Authors and Affiliations

  1. Russian Medical Academy of Continuing Professional Education, Russian Ministry of Health, Moscow, Russia

    O. V. Yakovleva, E. A. Lyashenko & O. S. Levin

  2. Sechenov First Moscow State Medical Institute (Sechenov University), Russian Ministry of Health, Moscow, Russia

    M. G. Poluektov

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  1. O. V. Yakovleva
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  2. M. G. Poluektov
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  3. E. A. Lyashenko
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  4. O. S. Levin
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Correspondence to O. V. Yakovleva.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 119, No. 4, Iss. 2, Insomnia, pp. 89–98, April, 2019.

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Yakovleva, O.V., Poluektov, M.G., Lyashenko, E.A. et al. Sleep and Cognitive Impairments in Neurodegenerative Diseases. Neurosci Behav Physi 50, 275–282 (2020). https://doi.org/10.1007/s11055-020-00898-y

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