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Parasomnias Associated with Disordered Arousal from Slow-Wave Sleep: Mechanism of Occurrence and Neurophysiological Characteristics

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This article discusses the current state of parasomnias associated with disorders of arousal from slow-wave sleep. The clinical picture and diagnosis of the condition are evaluated in detail. The stress is placed on the mechanisms producing types of parasomnias and characteristic changes in the CNS. The challenge of neurophysiological changes preceding the different linical signs of parasomnia and the concept of the local sleep as a physiological basis of parasomnias associated with disorders of arousal from slow-wave sleep is discussed, and current therapeutic approaches to these forms of parasomnia are assessed.

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References

  1. M. J. Sateia, “International Classification of Sleep Disorders – Third Edition,” Chest, 146, No. 5, 1387–1394 (2014), https://doi.org/10.1378/chest.14-0970.

    Article  Google Scholar 

  2. R. Lopez, I. Jaussent, S. Scholz, et al., “Functional impairment in adult sleepwalkers: a case-control study,” Sleep, 36, 345–351 (2013), https://doi.org/10.5665/sleep.2446.

    PubMed  PubMed Central  Google Scholar 

  3. D. Petit, M. Pennestri, J. Paquet, et al., “Childhood sleepwalking and sleep terrors: a longitudinal study of prevalence and familial aggregation,” JAMA Pediatr., 169, 653–658 (2015), https://doi.org/10.1001/jamapediatrics.2015.127.

    Article  Google Scholar 

  4. R. Lopez, I. Jaussent, and Y. Dauvilliers, “Pain in sleepwalking: a clinical enigma,” Sleep, 38, 1693–1698 (2015), https://doi.org/10.5665/sleep.5144.

    Article  Google Scholar 

  5. G. Uguccioni, J.-L. Golmard, A. N. de Fontreaux, et al., “Fight or flight? Dream content during sleepwalking/sleep terrors versus rapid eye movement sleep behavior disorder,” Sleep Med., 14, 391–398 (2013), https://doi.org/10.1016/j.sleep.2013.01.014.

    Article  Google Scholar 

  6. N. Di Fabio, R. Poryazova, M. Oberholzer, et al., “Sleepwalking, REM sleep behaviour disorder and overlap parasomnia in patients with Parkinson’s disease,” Eur. Neurol., 70, 297–303 (2013), https://doi.org/10.1159/000353378.

    Article  Google Scholar 

  7. Y. Dauvilliers, I. Arnulf, and E. Mignot, “Narcolepsy with cataplexy,” Lancet, 369, 499–511 (2007), https://doi.org/10.1016/s0140-6736(07)60237-2.

    Article  Google Scholar 

  8. N. Limousin, C. Dehais, O. Gout, et al., “A brainstem inflammatory lesion causing REM sleep behavior disorder and sleepwalking (para somnia overlap disorder),” Sleep Med., 10, 1059–1062 (2009), https://doi.org/10.1016/j.sleep.2008.12.006.

    Article  Google Scholar 

  9. C. A. Kushida, A. A. Clerk, C. M. Kirsch, et al., “Prolonged confusion with nocturnal wandering arising from NREM and REM sleep: a case report,” Sleep, 18, 757–764 (1995), https://doi.org/10.1093/sleep/18.9.757.

    CAS  PubMed  Google Scholar 

  10. M. Puligheddu, P. Congiu, I. Laccu, et al., “Overlap parasomnia disorder in a case of Creutzfeldt–Jakob disease,” Sleep Med., 36, 75–77 (2017), https://doi.org/10.1016/j.sleep.2017.05.014.

    Article  Google Scholar 

  11. L. Nobili, M. Ferrara, F. Moroni, et al., “Dissociated wake-like and sleep-like electrocortical activity during sleep,” Neuroimage, 58, 612–619 (2011), https://doi.org/10.1016/j.neuroimage.2011.06.032.

    Article  Google Scholar 

  12. L. Nobili, “Local aspects of sleep: observations from intracerebral recordings in humans,” Prog. Brain Res., 199, 219–232 (2012), https://doi.org/10.1016/j.ijpsycho.2012.06.177.

    Article  Google Scholar 

  13. A. Zadra, A. Desautels, D. Petit, and J. Montplaisir, “Somnambulism: clinical aspects and pathophysiological hypotheses,” Lancet Neurol., 12, 285–294 (2013), https://doi.org/10.1016/s1474-4422(12)70322-8.

    Article  Google Scholar 

  14. G. Uguccioni, O. Pallanca, J. L. Golmard, et al., “Is sleep-related verbal memory consolidation impaired in sleepwalkers?” J. Sleep Res., 24, 197–205 (2015), https://doi.org/10.1111/jsr.12219.

    Article  Google Scholar 

  15. R. Lopez, Y. Shen, S. Chenini, et al., “Diagnostic criteria for disorders of arousal: a videopolysomnographic assessment,” Ann. Neurol., 83, 341–351 (2018), https://doi.org/10.1002/ana.25153.

    Article  Google Scholar 

  16. O. Jaar, M. Pilon, J. Carrier, et al., “Analysis of slow-wave activity and slow-wave oscillations prior to somnambulism,” Sleep, 33, 1511–1516 (2010), https://doi.org/10.1093/sleep/33.11.1511.

    Article  Google Scholar 

  17. R. Perrault, J. Carrier, A. Desautels, et al., “Electroencephalographic slow waves prior to sleepwalking episodes,” Sleep Med., 15, 1468–1472 (2014), https://doi.org/10.1016/j.sleep.2014.07.020.

    Article  Google Scholar 

  18. C. Guilleminault, D. Poyares, F. A. Aftab, and L. Palombini, “Sleep and wakefulness in somnambulism: a spectral analysis study,” J. Psychosom. Res., 51, No. 2, 411–416 (2001), https://doi.org/10.1016/s0022-3999(01)00187-8.

    Article  CAS  Google Scholar 

  19. C. H. Schenck, J. A. Pareja, A. L. Patterson, and M. W. Mahowald, “Analysis of polysomnographic events surrounding 252 slow-wave sleep arousals in thirty-eight adults with injurious sleepwalking and sleep terrors,” J. Clin. Neurophysiol., 15, 159–166 (1998), https://doi.org/10.1097/00004691-199803000-00010.

    Article  CAS  Google Scholar 

  20. A. Zadra, M. Pilon, S. Joncas, et al., “Analysis of postarousal EEG activity during somnambulistic episodes,” J. Sleep Res., 13, 279–284 (2004), https://doi.org/10.1111/j.1365-2869.2004.00404.x.

    Article  Google Scholar 

  21. P. Januszko, S. Niemcewicz, T. Gajda, et al., “Sleepwalking episodes are preceded by arousal-related activation in the cingulate motor area: EEG current density imaging,” Clin. Neurophysiol., 127, 530–536 (2016), https://doi.org/10.1016/j.clinph.2015.01.014.

    Article  Google Scholar 

  22. A. Castelnovo, B. A. Riedner, R. F. Smith, et al., “Scalp and source power topography in sleepwalking and sleep terrors: a high-density EEG study,” Sleep, 39, 1815–1825 (2016), https://doi.org/10.5665/sleep.6162.

    Article  Google Scholar 

  23. V. V. Vyazovskiy, U. Olcese, E. C. Hanlon, et al., “Local sleep in awake rats,” Nature, 472, 443–447 (2011), https://doi.org/10.1038/nature10009.

    Article  CAS  Google Scholar 

  24. F. De Carli, P. Proserpio, E. Morrone, et al., “Activation of the motor cortex during phasic rapid eye movement sleep,” Ann. Neurol., 79, 326–330 (2016), https://doi.org/10.1002/ana.24556.

    Article  Google Scholar 

  25. M. E. Desjardins, J. Carrier, J. M. Lina, et al., “EEG functional connectivity prior to sleepwalking: Evidence of interplay between sleep and wakefulness,” Sleep, 40, No. 4, zsx024 (2017), https://doi.org/10.1093/sleep/zsx024.

  26. A. Heidbreder, A. Stefani, E. Brandauer, et al., “Gray matter abnormalities of the dorsal posterior cingulate in sleep walking,” Sleep Med., 36, 152–155 (2017), https://doi.org/10.1016/j.sleep.2017.05.007.

    Article  Google Scholar 

  27. C. Bassetti, S. Vella, F. Donati, et al., “SPECT during sleepwalking,” Lancet, 356, 484–485 (2000), https://doi.org/10.1016/s0140-6736(00)02561-7.

    Article  CAS  Google Scholar 

  28. M. E. Desjardins, A. A. Baril, J. P. Soucy, et al., “Altered brain perfusion patterns in wakefulness and slow-wave sleep in sleepwalkers,” Sleep, 41, No. 5, zsy039 (2018), https://doi.org/10.1093/sleep/zsy039.

  29. T. T. Dang-Vu, A. Zadra, M. A. Labelle, et al., “Sleep deprivation reveals altered brain perfusion patterns in somnambulism,” PLoS One, 10, e0133474 (2015), https://doi.org/10.1371/journal.pone.0133474.

    Article  Google Scholar 

  30. C. H. Schenck, J. A. Pareja, A. L. Patterson, and M. W. Mahowald, “Analysis of polysomnographic events surrounding 252 slow-wave sleep arousals in thirty-eight adults with injurious sleepwalking and sleep terrors,” J. Clin. Neurophysiol., 15, 159–166 (1998), https://doi.org/10.1097/00004691-199803000-00010.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Samara Sate Medical University, Russian Ministry of Health, Samara, Russia

    A. V. Zakharov, I. E. Poverennova, V. A. Kalinin & E. V. Khivintseva

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  1. A. V. Zakharov
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  2. I. E. Poverennova
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  3. V. A. Kalinin
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  4. E. V. Khivintseva
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Correspondence to A. V. Zakharov.

Additional information

Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 119, No. 4, Iss. 2, Insomnia, pp. 50–55, April, 2019.

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Zakharov, A.V., Poverennova, I.E., Kalinin, V.A. et al. Parasomnias Associated with Disordered Arousal from Slow-Wave Sleep: Mechanism of Occurrence and Neurophysiological Characteristics. Neurosci Behav Physi 50, 270–274 (2020). https://doi.org/10.1007/s11055-020-00897-z

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