Objectives. To study the neuroprotective properties of lithium ascorbate (LA) in in vivo and in vitro stress models. Materials and methods. Neurocytological and behavioral studies were run in models of stress in nerve cell cultures and experimental animals. Results. LA was shown to have a marked neuroprotective effect in conditions of glutamate-induced cytotoxicity in vitro and an adaptogenic effect on induction of stress in vivo. Conclusions. The results obtained here demonstrated that LA has high neuroprotective potential in stress induced in vivo and in vitro.
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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 116, No. 12, Iss. 1, pp. 86–91, December, 2016.
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Pronin, A.V., Gromova, O.A., Sardaryan, I.S. et al. The Adaptogenic and Neuroprotective Properties of Lithium Ascorbate. Neurosci Behav Physi 48, 409–415 (2018). https://doi.org/10.1007/s11055-018-0579-3
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DOI: https://doi.org/10.1007/s11055-018-0579-3