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Consolidation, Reactivation, and Reconsolidation of Memory

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This preview presents data on the consolidation and reconsolidation of memories for negative and positive events via reactivation (reminding) obtained using different experimental models. Particular attention is paid to the time windows during which amnestic and other treatments during memory consolidation/reconsolidation are effective. Similarities and differences between memory consolidation on initial learning and repeated consolidation (reconsolidation) on reactivation by a conditioned stimulus and context are discussed. Hypothetical concepts are presented in relation to the possibility of renewing memory on reconsolidation and various pathways of influencing it.

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  1. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia

    G. A. Grigor’yan & V. A. Markevich

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Correspondence to G. A. Grigor’yan.

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Translated from Zhurnal Vysshei Nervnoi Deyatel’nosti imeni I. P. Pavlova, Vol. 64, No. 2, pp. 123–136, March–April, 2014.

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Grigor’yan, G.A., Markevich, V.A. Consolidation, Reactivation, and Reconsolidation of Memory. Neurosci Behav Physi 45, 1019–1028 (2015). https://doi.org/10.1007/s11055-015-0181-x

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