Time series analysis methods were used to identify the characteristics of motor system activity to obtain objective assessments of the functional state of the pyramidal and extrapyramidal systems in humans. Voluntary control of isometric force as the motor output of a control system was used as a model of movement. An original noninvasive study methodology was used to measure isometric force as the motor output of the integrative activity of the CNS, along with contemporary time series analysis methods; these yielded new data for assessment of the activity of motor system structures in health and in a variety of neurodegenerative diseases of the CNS (Parkinson’s disease, multiple sclerosis), supplementing existing fundamental concepts in motor physiology and extending the potential of instrumented diagnosis of neuromotor dysfunctions.
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Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 98, No. 11, pp. 1416–1431, November, 2012.
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Aleksanyan, Z.A., Romanov, S.P. Measures of the Integrative Activity of the Motor System in Health and Pathological Neuromotor States. Neurosci Behav Physi 44, 793–803 (2014). https://doi.org/10.1007/s11055-014-9986-2
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DOI: https://doi.org/10.1007/s11055-014-9986-2