Skip to main content
Log in

Identification of the Minimal Dose of Na2EDTA Able to Stimulate Respiration in Rats during Hypothermia

  • Published:
Neuroscience and Behavioral Physiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. N. K. Arokina, “Stimulation of cutaneous thermoreceptors and cold shivering by injection of EDTA in profound hypothermia,” Sensor Sistemy, 16, No. 3, 238–244 (2002).

    Google Scholar 

  2. K. B. Aslanidi, G. V. Aslanidi, D. M. Vachadze, V. P. Zinchenko, Yu. A. Labas, and T. V. Potapova, “The possible involvement of ion stress in the cold death of cells,” Biol. Membrany, 14, No. 1, 50–64 (1997).

    CAS  Google Scholar 

  3. E. Darst, Ion-Selective Electrodes [Russian translation], Mir, Moscow (1972).

    Google Scholar 

  4. K. P. Ivanov, “Physiological blockade of the mechanisms of cold death. Recovery of physiological functions after profound, nearlethal hypothermia,” Usp. Fiziol. Nauk., 38, No. 2, 63–74 (2007).

    CAS  PubMed  Google Scholar 

  5. K. P. Ivanov, N. K. Arokina, M. F. Volkova, G. B. Morozov,V. N. Chikhman, and S. D. Solnushkin, “Blockade of the mechanisms of cold paralysis of physiological functions,” Ros. Fiziol. Zh. im. I. M. Sechenova, 86, No. 6, 692–702 (2000).

    CAS  Google Scholar 

  6. K. P. Ivanov, N. K. Arokina, and I. L. Potekhina, “Stimulation of physiological functions in rats in profound hypothermia without warming produced by intraventricular administration of EDTA solution,” Ros. Fiziol. Zh. im. I. M. Sechenova, 91, No. 3, 286–292 (2005).

    CAS  Google Scholar 

  7. M. D. Mashkovskii, Medicines [in Russian], Novaya Volna, Moscow (2000).

    Google Scholar 

  8. G. S. Fedorov, N. K. Arokina, and K. P. Ivanov, “Mechanisms of suppression of physiological functions in hypothermia and means of stimulating them without warming the body,” Ros. Fiziol. Zh. im. I. M. Sechenova, 92, No. 11, 1373–1381 (2006).

    CAS  Google Scholar 

  9. R. G. Boutilier, “Mechanisms of cell survival in hypoxia and hypothermia,” J. Exp. Biol., 204, No. 18, 3171–3181 (2001).

    CAS  PubMed  Google Scholar 

  10. E. Carafoli, “The calcium pumping ATPase of the plasma membrane,” Ann. Rev. Physiol., 53, 531–547 (1991).

    Article  CAS  Google Scholar 

  11. P. W. Hachachka, “Defense strategies against hypoxia and hypothermia,” Science, 231, No. 4755, 234–241 (1986).

    Article  Google Scholar 

  12. R. R. Kempainen and D. D. Brunette, “The evaluation and management of accidental hypothermia,” Respir. Car, 49, No. 2, 192–205 (2004).

    Google Scholar 

  13. T. Pozzan, R. Rizzuto, P. Volpe, and J. Meldolesi, “Molecular and cellular physiology of intracellular calcium stores,” Physiol. Rev., 74, No. 3, 595–636 (1994).

    CAS  PubMed  Google Scholar 

  14. J. M. Stocks, N. A. Taylor, M. J. Tipton, and J. E. Greenleaf, “Human physiological responses to cold exposure,” Aviat. Space Environ. Med., 75, No. 5, 444–457 (2004).

    PubMed  Google Scholar 

  15. S. O. Wang, E. G. Lakatta, H. Cheng, and Z. Q. Chou, “Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators,” J. Exp. Biol., 205, No. 19, 2957–2962 (2002).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. K. Arokina.

Additional information

Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 95, No. 7, pp. 779–785, July, 2009.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Arokina, N.K., Fedorov, G.S. Identification of the Minimal Dose of Na2EDTA Able to Stimulate Respiration in Rats during Hypothermia. Neurosci Behav Physi 40, 902–906 (2010). https://doi.org/10.1007/s11055-010-9343-z

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11055-010-9343-z

Keywords

Navigation