Skip to main content
Log in

Efficacy and Safety of Prolonged Immunomodulatory Treatment with Interferon Beta

  • Published:
Neuroscience and Behavioral Physiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. C. Confavreux, G. Aimard, and M. Devic, “Course and prognosis of multiple sclerosis assessed by computerized data processing of 349 patients,” Brain, 103, 281–300 (1980).

    Article  PubMed  CAS  Google Scholar 

  2. “European Study Group on Interferon β-1b in Secondary Progressive MS. Placebo-controlled multicenter randomised trial of interferon β-1b in treatment of secondary progressive multiple sclerosis,” Lancet, 352, 1491–1497 (1998).

    Google Scholar 

  3. G. Ebers, A. Traboulsee, D. Langdon, et al., “Final results from the interferon β-1b 16 year long-term follow-up study,” Poster presented at ECTRIMS, Madrid (2006), p. 666.

  4. IFNB Multiple Sclerosis Study Group, “Interferon β-1b is effective in relapsing-remitting multiple sclerosis. 1. Clinical results of multicenter, randomised, double-blind, placebo-controlled trial,” Neurology, 43, 655–661 (1993).

    Google Scholar 

  5. L. D. Jacobs, D. L. Cookfair, R. A. Rudick, et al., “Intramuscular interferon β-1a for disease progression in relapsing multiple sclerosis,” Ann. Neurol., 39, 285–294 (1996).

    Article  PubMed  CAS  Google Scholar 

  6. L. D. Jacobs, R. W. Beck, J. H. Simon, et al., “Intramuscular interferon β-1a therapy initiated during a first demyelinating event in multiple sclerosis CHAMPS Study Group,” New Eng. J. Med., 343, 898–904 (2000).

    Article  PubMed  CAS  Google Scholar 

  7. R. P. Kinkel, C. Kollman, P. O’Connor, et al., “CHAMPIONS Study Group. IM interferon β-1a delays definite multiple sclerosis 5 years after a first demyelinating event,” Neurology, 66, 678–684 (2006).

    Article  PubMed  Google Scholar 

  8. J. Kuhle, M. Hardmeier, M. D. Hooghe, et al., “On behalf of the EUSPMS long-term follow-up of European Study of interferon β-1b (EUSPMS) in secondary progressive MS,” Mult. Scler., 9, Supplement 1, 143 (2003).

    Google Scholar 

  9. L. Kappos, A. Traboulsee, C. Constaninescu, et al., “Long-term subcutaneous interferon (β-1a therapy in patients with relapsing-remitting MS,” Neurology, 67, 944–953 (2006).

    Article  PubMed  CAS  Google Scholar 

  10. B. Runmarker and O. Andersen, “Prognostic factors in multiple sclerosis incidence cohort with twenty-five years of follow-up,” Brain, 116, No. 1, 117–134 (1993).

    Article  PubMed  Google Scholar 

  11. R. A. Rudick, G. R. Cutter, M. Baier, et al., “Estimating long-term effects of disease-modifying drug therapy in multiple sclerosis patients,” Mult. Scler., 11, 626–634 (2005).

    Article  PubMed  CAS  Google Scholar 

  12. “PRISMS (Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis) Study Group. Randomized double-blind placebo-controlled study of interferon β-1a in relapsing- remitting multiple sclerosis,” Lancet, 352, 1498–1504 (1998).

    Google Scholar 

  13. “PRISMS Study Group and the University of British Columbia MS/MRI Analysis Group PRISMS-4: Long-term efficacy of interferon β-1a in relapsing MS,” Neurology, 56, 1628–1636 (2001).

    Google Scholar 

  14. “The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group. Interferon β-1b in the treatment of multiple sclerosis: final outcome of the randomised controlled trial,” Neurology, 45, 1277–1285 (1995).

    Google Scholar 

  15. B. G. Weinshenker, B. Bass, G. P. Rice, et al., “The natural history of multiple sclerosis: geographically based study. I. Clinical course and disability,” Brain, 112, No. 1, 133–146 (1989).

    Article  PubMed  Google Scholar 

  16. B. G. Weinshenker, “The natural history of multiple sclerosis,” Neurol. Clin., 13, 119–146 (1995).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 108, No. 4, pp. 24–26, April, 2008.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Demina, T.L., Khachanova, N.V., Davydovskaya, M.V. et al. Efficacy and Safety of Prolonged Immunomodulatory Treatment with Interferon Beta. Neurosci Behav Physi 39, 497–499 (2009). https://doi.org/10.1007/s11055-009-9151-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11055-009-9151-5

Keywords

Navigation