Neuroscience and Behavioral Physiology

, Volume 37, Issue 8, pp 755–759 | Cite as

Clinical-psychological characteristics of children with dysgenesis of the cerebellar vermis

  • M. Yu. Bobylova
  • A. S. Petrukhin
  • G. N. Dunaevskaya
  • S. V. Piliya
  • E. S. Il’ina
Article

Abstract

This report addresses behavioral abnormalities in children with cerebellar anomalies demonstrated on MRI scans. Published data are presented showing an interaction between cerebellar pathology and early childhood autism. The cerebellum is involved not only in movement coordination, but also in social adaptation and verbal communication. The genes expressed in the cerebellum during childhood are identical to those expressed in the hippocampus. We have observed 20 children with MRI-identified agenesis of the cerebellar vermis and behavioral abnormalities; children were aged 3–15 (mean 7.05) years and there were 12 males and eight females. A variety of autistic characteristics were identified in these children.

Key words

agenesis or hypoplasia of the cerebellar vermis autism delayed psychoverbal development mutism dysarthria hyperactivity MRI 

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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • M. Yu. Bobylova
    • 1
    • 2
  • A. S. Petrukhin
    • 1
    • 2
  • G. N. Dunaevskaya
    • 1
    • 2
  • S. V. Piliya
    • 1
    • 2
  • E. S. Il’ina
    • 1
    • 2
  1. 1.Russian State Medical UniversityRussia
  2. 2.Russian Pediatric Clinical HospitalMinistry of Health of the Russian FederationMoscow

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