Abstract
The neurotransmitter composition of neurons in the stellate ganglion of mice of different ages (neonatal and aged 10, 20, 30, and 60 days) was studied using an immunocytochemical method. Most of the neurons in the mice of these age groups contained tyrosine hydroxylase (TH). Most choline acetyltransferase (CAT)-positive neurons in neonatal and 10-day mice were also TH-positive. From birth and at all subsequent ages, there were increases in the proportion of cells contained TH and neuropeptide Y. The proportion of neurons containing vasoactive intestinal peptide and CAT increased to 10 days of life and then decreased. Somatostatin-and galanin-positive neurons were absent from all animals. Maturation of the set of neurotransmitters in stellate ganglia was complete by age two months.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
G. G. Avtandilov, Medical Morphology [in Russian], Meditsina, Moscow (1990).
A. F. Nozdrachev, “The chemical structure of a peripheral autonomic (visceral) reflex,” Usp. Fiziol. Nauk., 27, No. 2, 28–60 (1996).
A. D. Nozdrachev and M. M. Fadeev, The Stellate Ganglion. Structure and Function [in Russian], Nauka, St. Petersburg (2002).
V. S. Sheveleva, Evolution of the Functions of Sympathetic Ganglia in Ontogenesis [in Russian], Nauka, Leningrad (1977).
P. Cochard, M. Goldstein, and I. B. Black, “Initial development of the noradrenergic phenotype in autonomic neuroblasts of the rat embryo in vivo,” Dev. Biol., 71, 109–114 (1979).
U. Ernsberger, “The development of postganglionic sympathetic neurons: coordinating neuronal differentiation and diversification,” Auton. Neurosci. Basic Clin., 94, 1–13 (2001).
U. Ernsberger and H. Rohrer, “Development of the cholinergic neurotransmitter phenotype in postganglionic sympathetic neurons,” Cell Tiss. Res., 297, 339–361 (1999).
I. L. Gibbins, “Vasomotor, pilomotor and secretomotor neurons distinguished by size and neuropeptide content in superior cervical ganglia of mice,” J. Auton. Nerv. Syst., 34, 171–183 (1991).
L. Klimaschewski, W. Kummer, and C. Heym, “Localization, regulation and function of neurotransmitters and neuromodulators in cervical sympathetic ganglia,” Microsc. Res. Tech., 35, 44–68 (1996).
P. M. Masliukov, V. A. Pankov, A. A. Strelkov, et al., “Morphological features of neurons innervating different viscera in the cat stellate ganglion in postnatal ontogenesis,” Auton. Neurosci. Basic Clin., 84, 169–175 (2000).
P. M. Masliukov, V. V. Shilkin, A. D. Nozdrachev, and J.-P. Timmermans, “Histochemical features of neurons in the cat stellate ganglion during postnatal ontogenesis,” Auton. Neurosci. Basic Clin., 106, 84–90 (2003).
M. A. Morales, K. Holmberg, Z. Q. Xu, et al., “Localization of choline acetyltransferase in rat peripheral sympathetic neurons and its coexistence with nitric oxide synthase and neuropeptides,” Proc. Natl. Acad. Sci. USA, 92, 11819–11823 (1995).
V. Roudenok, “Changes in the expression of neuropeptide Y (NPY) during maturation of human sympathetic ganglionic neurons: correlations with tyrosine hydroxylase immunoreactivity,” Ann. Anat., 182, 515–519 (2000).
Author information
Authors and Affiliations
Additional information
Director: Professor V. N. Volovenko
__________
Translated from Morfologiya, Vol. 128, No. 5, pp. 41–44, September–October, 2005.
Rights and permissions
About this article
Cite this article
Maslyukov, P.M., Shilkin, V.V. & Timmermans, JP. Immunocytochemical characteristics of neurons in the stellate ganglion of the sympathetic trunk in mice during postnatal ontogenesis. Neurosci Behav Physiol 36, 851–855 (2006). https://doi.org/10.1007/s11055-006-0097-6
Received:
Issue Date:
DOI: https://doi.org/10.1007/s11055-006-0097-6