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Spectroscopic analysis of the riboflavin—serum albumins interaction on silver nanoparticles

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Abstract

Spectrophotometric behavior of riboflavin (RF) adsorbed on silver nanoparticles as well as its interaction with two serum albumins, BSA and HSA, respectively, has been evidenced. The time evolution of the plasmonic features of the complexes formed by RF/BSA/HSA and Ag(0) nanoparticles having an average diameter of 10.0 ± 2.0 nm have been investigated by UV–Vis absorption spectroscopy. Using steady-state and time-resolved fluorescence spectroscopy, the structure, stability, and dynamics of the serum albumins have been studied. The efficiency of energy transfer process between RF and serum albumins on silver nanoparticles has been estimated. A reaction mechanism of RF with silver nanoparticles is also proposed and the results are discussed with relevance to the involvement of the silver nanoparticles to the redox process of RF and to the RF–serum albumins interaction into a silver nanoparticles complex.

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Acknowledgments

This study was a part of the research project proposal, UEFISCDI, project number PN-II-RU-TE-2012-3-0055. This study was also performed in the frame of the Romanian Academy programme and II; 8 theme of the INFRANANOCHEM project.

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Authors and Affiliations

  1. Romanian Academy, Institute of Physical Chemistry “Ilie Murgulescu”, Splaiul Independentei 202, Bucharest, 060021, Romania

    Mariana Voicescu & Daniel G. Angelescu

  2. Department of Physical Chemistry, University of Bucharest, Bd. Regina Elisabeta 4-12, Bucharest, 030018, Romania

    Sorana Ionescu

  3. Institute of Atomic Physics, National Institute of Materials Physics, Magurele, 077125, Romania

    Valentin S. Teodorescu

Authors
  1. Mariana Voicescu
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  2. Daniel G. Angelescu
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  3. Sorana Ionescu
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  4. Valentin S. Teodorescu
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Correspondence to Mariana Voicescu.

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Voicescu, M., Angelescu, D.G., Ionescu, S. et al. Spectroscopic analysis of the riboflavin—serum albumins interaction on silver nanoparticles. J Nanopart Res 15, 1555 (2013). https://doi.org/10.1007/s11051-013-1555-z

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  • DOI: https://doi.org/10.1007/s11051-013-1555-z

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