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One-step synthesis of bioactive glass by spray pyrolysis

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Abstract

Bioactive glasses (BGs) have recently received more attention from biologists and engineers because of their potential applications in bone implants. The sol–gel process is one of the most popular methods for fabricating BGs, and has been used to produce BGs for years. However, the sol–gel process has the disadvantages of discontinuous processing and a long processing time. This study presented a one-step spray pyrolysis (SP) synthesis method to overcome these disadvantages. This SP method has synthesized spherical bioactive glass (SBG) and mesoporous bioactive glass (MBG) particles using Si-, Ca- and P-based precursors. This study used transmission electron microscopy, selected area electron diffraction and X-ray dispersive spectroscopy to characterize the microstructure, crystallographic structure, and chemical composition for the BG particles. In addition, in vitro bioactive tests showed the formation of hydroxyl apatite layers on SBG and MBG particles after immersion in simulated body fluid for 5 h. Experimental results show the SP formation mechanisms of SBG and MBG particles.

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Acknowledgments

The authors acknowledge the financial support from National Taiwan University of Science and Technology (Grant No. 100H451201) and from the National Science Council of Taiwan (Grant No. NSC 101-2628-E-011-008-MY2).

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Authors and Affiliations

  1. Department of Materials Science and Engineering, National Taiwan University of Science and Technology, 43, Sec. 4 Keelung Road, Taipei, 10607, Taiwan

    Shao-Ju Shih, Yu-Jen Chou & I-Chen Chien

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  1. Shao-Ju Shih
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  2. Yu-Jen Chou
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  3. I-Chen Chien
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Correspondence to Shao-Ju Shih.

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Shih, SJ., Chou, YJ. & Chien, IC. One-step synthesis of bioactive glass by spray pyrolysis. J Nanopart Res 14, 1299 (2012). https://doi.org/10.1007/s11051-012-1299-1

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