Size response of an SMPS–APS system to commercial multi-walled carbon nanotubes
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Carbon nanotubes (CNTs) are representative-engineered nanomaterials with unique properties. The safe production of CNTs urgently requires reliable tools to assess inhalation exposure. In this study, on-line aerosol instruments were employed to detect the release of multi-walled CNTs (MWCNTs) in workplace environments. The size responses of aerosol instruments consisting of both a scanning mobility particle sizer (SMPS) and an aerodynamic particle sizer (APS) were examined using five types of commercial MWCNTs. A MWCNT solution and powder were aerosolized using atomizing and shaking methods, respectively. Regardless of the phase and purity, the aerosolized MWCNTs showed consistent size distributions with both SMPS and APS. The SMPS and APS measurements revealed a dominant broad peak at approximately 200–400 nm and a distinct narrow peak at approximately 2 μm, respectively. Comparing with field application of the two aerosol instruments, the APS response could be a fingerprint of the MWCNTs in a real workplace environment. A modification of the atomizing method is recommended for the long-term inhalation toxicity studies.
KeywordsAerosol Atomizing EHS Inhalation exposure Multi-walled carbon nanotubes (MWCNTs) Occupational health Shaking Size response
- Bae GN, Lee SB, Park SM (2007) Vehicle-related fine particulate air pollution in Seoul, Korea. Asian J Atmos Environ 1(1):1–8Google Scholar
- Mülhopt S, Paur H-R, Diabaté S, Krug HF (2007) In vitro testing of inhalable fly ash at the air–liquid interface. Advanced environmental monitoring. Springer, Netherlands, pp 402–414Google Scholar
- Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WAH, Seaton A, Stone V, Brown S, MacNee W, Donaldson K (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol. doi:10.1038/nnano.2008.111
- Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorerlik O, Arepalli S, Hubbs F, Mercer RR, Keohavong P, Sussman N, Jin J, Yin J, Stone S, Chen BT, Deye G, Maynard AD, Castranova V, Baron PA, Kagan VE (2008) Inhalation versus aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung Cell Mol Physiol 295(4):L552–L565CrossRefPubMedGoogle Scholar