Journal of Nanoparticle Research

, Volume 11, Issue 3, pp 691–699 | Cite as

In situ processing and properties of nanostructured hydroxyapatite/alginate composite

Research Paper


A series of hydroxyapatite/alginate (HA/Alg) nanocomposites with alginate amounts varying from 10 to 40 wt% were prepared through in situ hybridization technique. The inorganic phase in the composites was carbonate-substituted HA with low crystallinity. The crystallinity of HA decreased with the increase of alginate content. HA crystallites were needle-like in shape with a typical size of 20 to 50 nm in length and 5 nm in width. FT-IR spectroscopy indicated that the chemical interaction occurred between the mineral phase and the polymer matrix. As compared to pure HA without alginate, the composites showed more homogeneous microstructures, where HA nanocrystals were well embedded in alginate matrix. Among all the samples, the composite containing 30 wt% alginate exhibited a highly ordered three-dimensional network, similar to natural bone’s microstructure.


Hydroxyapatite Alginate Nanocomposite In situ hybridization Microstructure Nanocrystals Nanomaterials 


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  1. 1.China National Academy of Nanotechnology & EngineeringTianjinChina
  2. 2.Department of Chemical Machinery, School of Chemical EngineeringDalian University of TechnologyDalainChina
  3. 3.Key Laboratory for Ultrafine Materials of Ministry of EducationEast China University of Science and TechnologyShanghaiChina

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