Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissues caused by different melanized fungi. The disease occurs worldwide, particularly in tropical and subtropical regions but not reported in Vietnam.
A 47-year-old women was admitted to hospital 103, Hanoi, Vietnam, with a 10-year lasting lesion on backside of her right shank. Diagnosis of chromoblastomycosis was made after discovery of a muriform cell in histopathological examination. A black, slow-growth fungus was isolated and identified as Fonsecaea pedrosoi after molecular analysis. After 1-month treatment with itraconazole, the lesion has significant improvement.
This is the first case of chromoblastomycosis caused by Fonsecaea pedrosoi reported in Vietnam.
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Polymerase chain reaction
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The authors are grateful to Mr. Robert Mayrhofer and Ms. Linh Khanh Le for revising the English text.
KLN and NAD conducted the study, as well as morphological and molecular analyses of the isolated strain. MHP collected clinical data. TTV made the histopathological examination. TAL designed the study and created the final draft of the manuscript. All authors read and approved the final manuscript.
Conflict of interest
The authors declare that they have no competing interests.
Availability of Data and Material
The sequence generated and analyzed during the current study is available in the GenBank under the code MF MF173064.
Consent for Publication
The authors agreed to publish this article in Mycopathologia.
Ethics Approval and Consent to Participate
Written informed consent was obtained from the patient for the publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.
Handling Editor: Yuping Ran.
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Le, TA., Nguyen, KL., Pham, MH. et al. Case Report: A Case of Chromoblastomycosis Caused by Fonsecaea pedrosoi in Vietnam. Mycopathologia 184, 115–119 (2019). https://doi.org/10.1007/s11046-018-0284-3
- Case report
- Fonsecaea pedrosoi
- Molecular analysis