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Dermatomycoses Due to Nannizzia praecox (Formerly Microsporum praecox) in Germany: Case Reports and Review of the Literature

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Abstract

Nannizzia praecox, formerly known as Microsporum praecox, is a geophilic dermatophyte. Up to now 31 cases of human tinea have been reported in the literature, most of them with an inflammatory course. Three recent cases diagnosed in Germany within 1 year suggest that the fungus might be a more common cause of human dermatophytosis than reported so far. This might be based on the fact that N. praecox is often found in an equine environment and that horse riding is becoming more popular recently.

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References

  1. De Hoog GS, Dukik K, Monod M, Packeu A, Stubbe D, Hendrickx M, Kupsch C, Stielow JB, Freeke J, Göker M, Rezaei-Matehkolaei A, Mirhendi H, Gräser Y. Toward a novel multilocus phylogenetic taxonomy for the dermatophytes. Mycopathologia. 2017;182:5–31.

    Article  PubMed  Google Scholar 

  2. Alanio A, Romand S, Penso-Assathiany D, Foulet F, Botterel F. Microsporum praecox: molecular identification of a new case and review of the literature. Mycopathologia. 2011;171:61–5.

    Article  PubMed  Google Scholar 

  3. Badillet G, Castillo S, Ghouti C. Isolement à Paris de Microsporum praecox. Bull Soc Fr Mycol Med. 1978;7:199–304.

    Google Scholar 

  4. Badillet G, Rush-Munro FM, Ouaknine D. Quelques précisions sur Microsporum praecox. Bulletin de la Société Française de Mycologie Médicale. 1980;9:5–9.

    Google Scholar 

  5. Weitzman I, McMillen S. Isolation in the United States of a culture resembling M. praecox. Mycopathologia. 1980;70:181–6.

    Article  CAS  PubMed  Google Scholar 

  6. De Vroey C, Wuytack-Raes C, Fossoul F. Isolation of saprophytic Microsporum praecox Rivalier from sites associated with horses. Sabouraudia. 1983;21:255–7.

    Article  PubMed  Google Scholar 

  7. Basset M, Kremer M, Koenig H, Ball C, Ismail MT, Waller J. Les champignons de la peau et des phanéres en Alsace. Bull Soc Fr Mycol Med. 1984;13:329–32.

    Google Scholar 

  8. Peyron F, Lebeau B, Grillot R, Aguilaniu F, Goullier A, Badillet G. Epidermatophytie à Microsporum praecox e´voquant un eczema de contact. Bull Soc Fr Mycol Med. 1986;15:197–200.

    Google Scholar 

  9. Contet-Audonneau N, Boniatsi L, Teillac D, Bordigoni C, Cherrier P, Badillet G. Trois nouvelles souches de Microsporum praecox isole´es en France. Bull Soc Fr Mycol Med. 1988;17:159–62.

    Google Scholar 

  10. Phelippot R, Feuilhade de Chauvin M, Michel Y, Pietrini P, Teillac D, Boniatsi L, Badillet G. Microsporum praecox: apropos of 4 cases. Ann Dermatol Venereol. 1988;115:1154–6.

    CAS  PubMed  Google Scholar 

  11. Avram A, Gauchy O, Blanchet P, Buot G. Trois cas de Dermatophytie à Microsporum praecox. Bull Soc Fr Mycol Méd. 1988;17:329–34.

    Google Scholar 

  12. Padhye AA, Detweiler JG, Frumkin A, Bulmer GS, Ajello L, McGinnis MR. Tinea capitis caused by Microsporum praecox in a patient with sickle cell anaemia. J Med Vet Mycol. 1989;27:313–7.

    Article  CAS  PubMed  Google Scholar 

  13. Badillet G. Dermatophytes et pseudo-dermatophytes. Biopathologiste. 1993;27:11–6.

    Google Scholar 

  14. Degeilh B, Contet-Audonneau N, Chevrier S, Guiguen C. A propos de trois nouveaux cas de dermatophytie à Microsporum praecox, revue des cas de la litterature des cas humains. J Mycol Med. 1994;4:175–8.

    Google Scholar 

  15. Buzina W, Ginter-Hanselmayer G. Microsporum praecox in Austria. Unpublished, submitted to NCBI. http://www.ncbi.nlm.nih.gov/genomes/MICROBES/microbial_taxtree.html, 21 June 2016, 20.00 Uhr

  16. Mayser P, Handrick W, Nenoff P. Sport-assoziierte Dermatophytosen—ein Überblick. Hautarzt. 2016;67:680–8.

    Article  CAS  PubMed  Google Scholar 

  17. Nenoff P, Overbeck C, Uhrlaß S, Krüger C, Gräser Y. Tinea corporis due to the rare geophilic dermatophyte Microsporum praecox. Hautarzt. 2017;68(5):396–402.

    Article  CAS  PubMed  Google Scholar 

  18. De Hoog GS, Guarro J, Gené J, Figueras MJ. Atlas of clinical fungi. 4rd Edition, USB Version, Centraalbureau voor Schimmelcultures. Reus: Universitat Rovira i Virgili; 2014.

    Google Scholar 

  19. Land GA. The genus Microsporum. In: Kane J, Summerbell R, Sigler L, Krajden S, Land GA, editors. Laboratory handbook of dermatophytes. A clinical guide and handbook of dermatophytes and other filamentous fungi from skin, hair, and nails. Belmont: Star Publishing Company; 1997. p. 193–211.

    Google Scholar 

  20. Kanbe T, Suzuki Y, Kamiya A, Mochizuki T, Fujihiro M, Kikuchi A. PCR-based identification of common dermatophyte species using primer sets specific for the DNA topoisomerase II genes. J Dermatol Sci. 2003;32:151–61.

    Article  CAS  PubMed  Google Scholar 

  21. Wiegand C, Mugisha P, Mulyowa GK, Elsner P, Hipler UC, Gräser Y, Uhrlaß S, Nenoff P. Identification of the causative dermatophyte of tinea capitis in children attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and comparison with conventional mycological diagnostic methods. Med Mycol. 2017;55(6):660–8.

    PubMed  Google Scholar 

  22. Mirhendi H, Makimura K, de Hoog GS, Rezaei-Matehkolaei A, Najafzadeh MJ, Umeda Y, Ahmadi B. Translation elongation factor 1-α gene as a potential taxonomic and identification marker in dermatophytes. Med Mycol. 2015;53:215–24.

    Article  CAS  PubMed  Google Scholar 

  23. Makimura K, Tamura Y, Mochizuki T, Hasegawa A, Tajiri Y, Hanazawa R, Uchida K, Saito H, Yamaguchi H. Phylogenetic classification and species identification of dermatophyte strains based on DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions. J Clin Microbiol. 1999;37:920–4.

    CAS  PubMed  PubMed Central  Google Scholar 

  24. Rivalier E. Description de Sabouraudites praecox nova species suivie de remarques sur le genre Sabouraudites [Description of Sabouraudites praecox n.sp. and remarks on the genus Sabouraudites]. Ann Inst Pasteur. 1954;86:276–84.

    CAS  Google Scholar 

  25. Rivalier E. Microsporum praecox. Bulletin de la Société Française de Mycologie Médicale. 1978;7:297.

    Google Scholar 

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Acknowledgements

We thank Boris Coonen, Mönchengladbach, for careful assistance in microscopic and cultural characterization of the strains and for MALDI-TOF MS analysis. Daniela Winkens, Mönchengladbach, has done DNA sequencing of M. praecox strain number three. We are grateful to Uwe Schossig, photographer from Leipzig, for excellent macroscopic pictures of the fungal colonies.

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Authors and Affiliations

  1. Laboratory for Medical Microbiology, Mölbiser Hauptstraße 8, 04571, Rötha/OT Mölbis, Germany

    Silke Uhrlaß, Daniela Koch, Constanze Krüger & Pietro Nenoff

  2. Hofmannstr. 11, Biebertal, Germany

    Peter Mayser

  3. Laboratory Dr. Stein and Colleagues, Medical Microbiology, Tomphecke 45, 41169, Mönchengladbach, Germany

    Roman Schwarz

  4. Dermatological Office Irene Korfmann, Geilenkirchen, Germany

    Irene Korfmann

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  1. Silke Uhrlaß
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  2. Peter Mayser
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  3. Roman Schwarz
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  4. Daniela Koch
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  5. Constanze Krüger
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  6. Irene Korfmann
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  7. Pietro Nenoff
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Correspondence to Pietro Nenoff.

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Research Involving Human Participants and/or Animals

All applicable international, national and/or institutional guidelines for the care and use of animals were followed. This article does not contain any studies with human participants performed by any of the authors. This article does not contain any studies with animals performed by any of the authors.

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Uhrlaß, S., Mayser, P., Schwarz, R. et al. Dermatomycoses Due to Nannizzia praecox (Formerly Microsporum praecox) in Germany: Case Reports and Review of the Literature. Mycopathologia 183, 391–398 (2018). https://doi.org/10.1007/s11046-017-0213-x

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