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Primary Cutaneous Mucormycosis Caused by Rhizopus oryzae: A Case Report and Review of Literature

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Abstract

Mucormycosis is an invasive infection caused by opportunistic fungi. Rhizopus, Lichtheimia, Mucor and Rhizomucor are the most common isolated genera. Primary cutaneous mucormycosis is usually related to traumatic injuries, but immunocompromised cases are associated with underlying conditions such as diabetes mellitus and malignancies. The treatment of choice is surgical debridement and liposomal amphotericin B. We present a 40-year-old male with fever and a painful necrotic lesion on the middle back and history of poorly controlled diabetes mellitus. Rhizopus oryzae was isolated and identified using an internal transcribed spacer regions ITS1 and ITS2. An initial good response to treatment was observed; however, 7 days later a diabetic ketoacidosis due to poor adherence to treatment caused a lethal outcome.

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Acknowledgements

We thank Cecilia González de Cossio and María Fernanda Ortega-Springall for her excellent medical assistance.

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Authors and Affiliations

  1. Servicio de Dermatología, Hospital General Dr. Manuel Gea González, 14080, Tlalpan, Mexico

    Erika Rodríguez-Lobato & Lourdes Ramírez-Hobak

  2. Departamento Medicina Interna, Hospital General Dr. Manuel Gea González, 14080, Tlalpan, Mexico

    Jorge E. Aquino-Matus

  3. Departamento de Infectología, Hospital General Dr. Manuel Gea González, 14080, Tlalpan, Mexico

    Juan P. Ramírez-Hinojosa & Víctor H. Lozano-Fernández

  4. Laboratorio de Bacteriología Intestinal, Hospital Infantil de México Dr. Federico Gómez, 06720, Cuauhtémoc, Mexico

    Juan Xicohtencatl-Cortes

  5. Departamento de Ecología de Agentes Patógenos, Hospital General Dr. Manuel Gea González, Sección XVI, 14080, Tlalpan, Mexico

    Rigoberto Hernández-Castro

  6. Sección de Micología, Hospital General Dr. Manuel Gea González, Sección XVI, 14080, Tlalpan, Mexico

    Roberto Arenas

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  1. Erika Rodríguez-Lobato
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  2. Lourdes Ramírez-Hobak
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  3. Jorge E. Aquino-Matus
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Correspondence to Rigoberto Hernández-Castro.

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Rodríguez-Lobato, E., Ramírez-Hobak, L., Aquino-Matus, J.E. et al. Primary Cutaneous Mucormycosis Caused by Rhizopus oryzae: A Case Report and Review of Literature. Mycopathologia 182, 387–392 (2017). https://doi.org/10.1007/s11046-016-0084-6

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  • DOI: https://doi.org/10.1007/s11046-016-0084-6

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